We rather saw a slight trend towards a decrease in cAMP release in stretched Cav3KO trabeculae after both β 1 AR and β 2 AR stimulation, though this trend did not reach statistical significance.
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Female sex showed a trend toward lower mortality risk, though this did not reach statistical significance (adjusted OR 0.70; 95% CI 0.48–1.03; p = 0.073).
It should also be added that while the association between PKC δ and disease-free interval did not reach statistical significance, there was a trend towards significance, that is the P -values were 0.074 and 0.052 using univariate and multivariate analyses, respectively.
low) showed a trend toward better OS but did not reach statistical significance (univariate HR = 0.695; 95% CI, 0.398–1.216; P = 0.202; multivariate HR = 0.889; 95% CI, 0.485–1.630; P = 0.703) (Fig. 5 g; Supplementary Fig. 7 g).
The children with active disease showed a trend toward higher numbers of time-intensity-curve shapes 3 and 4 compared to the children with inactive disease, but did not reach statistical significance ( P = 0.310 and P = 0.166).
In the overall analysis, 0 % anti-inflammatory intake showed a trend of reduced AD-specific mortality although its did not reach statistical significance after full adjustment (HR 3.04, 95 % CI 0.74–12.46 vs. ≥10 % intake; p>0.05).
In COPD cells, expression of both HOXA1 and HOXB2 showed an increasing trend with time of culturing, which did not reach statistical significance.
The 30-d mortality in the survival analysis showed a trend of lower risk in the EKD group than the ESD group (HR, 0.416; 95% CI, 0.122–1.413), although this result did not reach statistical significance ( P = 0.160; Fig. 2 A).
A history of hypertension showed a trend toward a negative association that approached, but did not reach statistical significance (adjusted OR = 0.424, 95% CI: 0.178–1.009; p = 0.052).
Although there was an increasing trend of HR of the 5-year OS of patients with CRC with the increasing number of hypermethylated genes in normal tissue, this difference did not reach statistical significance ( P = 0.33) (Table 3 ).
5 , 6 , 24 Although it did not reach statistical significance, we noted a nonsignificant trend toward fewer complications among our MIE patients.
a clear trendgold
The difference between obese and non-obese patients in the higher SML group showed a clear trend but did not reach statistical significance(median CSS: 605.0 days vs. 1196.0 days, P = 0.330, Fig. 4 b).
Furthermore, the correlation between the TyG index and αS-SAA parameters—TTT and T50%—did not reach statistical significance but showed a trend-level association(Additional file: Figure S3 ).
Patients who empirically received an appropriate antibiotic showed a trend toward better survival (HR: 0.24, CI up to 1.86), but this did not reach statistical significance ( p = 0.20).
The standard-intensity group showed a trend toward increased risk, but this did not reach statistical significance (HR = 3.876, 95% CI: 0.846–17.758, P = 0.081).
An increasing trend in proteinuria with higher sodium intake was observed in individuals with diabetes, although this did not reach statistical significance ( S1A and S1B Figs ).
a positive trendgold
A positive trend between β-carotene and CSF TNF-α was also observed, however this did not reach statistical significance ( P = 0.17).
The levels of Cr/PCr, acetate and glutamate showed a trend towards an increase, while myo-inositol showed a trend towards a decrease in CAL R compared with CAL S tumours but these effects did not reach statistical significance. 31 P NMR analysis of CAL S and CAL R tumour extracts corroborated the elevation in GPC and PCr levels and additionally revealed a rise in glycerophosphoethanolamine (GPE) and a fall in phosphoethanolamine (PE) levels in CAL R relative to CAL S tumours ( Table 1 and Figure 2C ).
Similarly, biologic therapy in the severe asthma subgroup showed a trend towards increased remission, but this did not reach statistical significance ( Fig. 2 A).
The dendritic expansion of Purkinje cells transfected with RGS8-GFP showed a trend toward decreasing dendritic tree size compared to non-transfected Purkinje cells in same culture well or Purkinje cells transfected with GFP tag alone, but the reduction did not reach statistical significance.
The C/F group showed a trend towards higher hepatic triglyceride content compared to the C and GCRB/F groups, although this difference did not reach statistical significance.
In the present study, inclusion of a single lap belt PT in addition to the shoulder belt PT showed a trend of reducing submarining risk for the reclined FE-HBMs, although this effect did not reach statistical significance for the simulation sample (p = 0.22).
771.7 ± 35.1, p = 0.182) showed a trend toward higher values in the RML group, but these differences did not reach statistical significance.
Similarly, vGlut2 and mGluR1 showed a trend toward increased expression in the VDD group compared to the VD‐ hypo and VD‐ hyper groups, although these changes did not reach statistical significance (Figure 5L,M , one‐way ANOVA with Tukey's multiple comparisons post hoc test).
Although these findings did not reach statistical significance ( p = 0.088), a decreasing trend in risk with increasing zinc intake was noted.