“did not reach statistical significance”

While female children and those with mothers who had lower educational levels showed a trend towards higher seizure frequency, these connections did not reach statistical significance.

Although the between-group difference in gender distribution did not reach statistical significance (p = 0.067), the near-significant result suggested a potential influence on outcomes; therefore, gender was included as a covariate in subsequent analyses.

Offspring brain mtDNAcn showed a negative trend but did not reach statistical significance.

Although hStrO neurons showed a trend toward increased excitability upon CGP treatment, this change did not reach statistical significance (fig.

Specifically, benralizumab demonstrated a borderline significant reduction in exacerbation risk (rate ratio 0.92; 95% CI: 0.85-1.00), while mepolizumab exhibited a trend toward lower exacerbation risk that did not reach statistical significance (rate ratio 0.90; 95% CI: 0.77-1.06) ( 44 ).

The continuous NRI showed a positive trend (0.121) but did not reach statistical significance.

Unadjusted Kaplan–Meier curves showed a trend toward prolonged intracranial control in the WBRT arm, although the difference did not reach statistical significance ( Figure 2a , P = .080).

Furthermore, the hM4Di group spent more time in the open arms and showed a trend toward an increased number of open arms entries, although the latter did not reach statistical significance (Fig.

Finally, children treated with premixed insulin demonstrated a nonsignificant trend toward poorer glycemic control compared with those receiving NPH/regular insulin; however, this association did not reach statistical significance.

In contrast, among patients who received mastectomy or conventional fractionation, proton therapy showed a trend toward lower rate of radiographic pneumonitis; however, the difference did not reach statistical significance.

HDL levels showed a decreasing trend, but this change did not reach statistical significance.

Furthermore, in the Cox proportional hazards regression adjusted for age, decreased LA strain showed a trend toward association with the primary outcome, although this did not reach statistical significance (HR, 1.90 [95% CI, 0.92–3.90], P =0.081).

Significant differences were observed between the two subtypes in terms of sex ( p = 0.003), PSQI ( p = 0.0004), SAS ( p < 0.0001), and SDS ( p < 0.0001), whereas age showed a trend toward difference but did not reach statistical significance ( p = 0.064) ( Table 2 ).

In this cohort, DLRT showed a trend towards better survival than CLSLRT in RLD patient undergoing lung retransplantation for BOS, although this did not reach statistical significance.

Co-localization of BNIP3, BNIP3L and phospho-BNIP3L with mitochondria basally showed a trend toward being reduced, however, due to large variability between both controls and patients this did not reach statistical significance ( Figure 5 and Supplementary Figure 6 ).

The length of hospital stay showed a slight increase in the risk of infection-related mortality, with an odds ratio of 1.014 (95% CI: 0.998–1.030); however, this association did not reach statistical significance (p=0.078), indicating only a trend towards significance.

For the primary endpoint of all-cause mortality or HF readmission, the NSAIDs-related group showed a trend toward improved outcomes, although the difference did not reach statistical significance (hazard ratio [HR] 0.569, 95% confidence interval [CI] 0.289–1.118; p = 0.102).

Notably, the low-dose rhCol III group (5 μg/mL) showed a trend toward reduced ROS fluorescence but did not reach statistical significance ( p = 0.0554), which may reflect a smaller effect size at low exposure, limited statistical power, and the known methodological limitations and sensitivity of commonly used fluorescent probes ( 68 , 69 ).

ACT scores showed a favorable trend in both groups, with a medium between-group effect size favoring the intervention (d = 0.42), although this did not reach statistical significance.

Concerning the intra-group analysis, although the EBWG showed a trend towards improvement in overall VAS, the difference between T0 and T2 did not reach statistical significance ( p = 0.074).

In contrast, although a decreasing trend in spheroid area was observed in the H2452 and 211H cell lines, these changes did not reach statistical significance (Figure 9 ). 4 Discussion This study demonstrated that inhibition of VPS34 by SAR405 significantly suppressed cell viability in pleural mesothelioma cell lines.

The likelihood of discussing menstrual issues with healthcare workers showed a positive trend toward better knowledge, though this association approached but did not reach statistical significance (OR = 1.7, 95% CI: 0.9–3.1, p = 0.065).

Although some markers did not reach statistical significance, SOF10 showed a trend toward suppressing TGF-β downstream targets Serpine1 , Col1a1 , and Col3a1 (Fig. 3d ).

Similarly, while CFU-E colony numbers showed a trend of increase with SRT2104 treatment (no SRT2104, 27.1%±4.7%; SRT2104, 35.7%±8.3%), this difference also did not reach statistical significance ( Fig. 4A ).

In the independent GEO cohort GSE39582 , DMBX1 expression showed a trend toward higher levels in colorectal cancer tissues compared with normal mucosa, although the difference did not reach statistical significance (Wilcoxon rank-sum test, p = 0.083).