“did not reach statistical significance”

The results showed that the proportion of S-phase cells exhibited an increasing trend but did not reach statistical significance, suggesting that the anti-ageing mechanism of cAMP did not depend on enhanced cell proliferation ( Fig. 3A ).

However, only two studies reported OS outcomes, which showed a trend toward benefit but did not reach statistical significance (HR=0.80, 95% CI=0.58–1.11; Figure 4D ).

A clear trend toward increased CEBPB mRNA m6A‐levels upon FTO knockdown was observed that did not reach statistical significance because of high experimental variation (Fig. 8G ).

The level of APLP1β27 showed a trend towards decreased levels in a dose-dependent manner in response to treatment but it did not reach statistical significance for either of the doses (Fig. 4f ).

Interestingly, 5 out of 8 patients showed a trend of increasing in Dll4 expression but the difference did not reach statistical significance ( Fig 7C ).

The 20A3R construct also showed a trend toward increased propagation compared to the WT construct, though this did not reach statistical significance ( Figure 2C ).

BCR-activated B cells also showed a strong trend for increased MHCII expression after coculture with MCs, although this finding did not reach statistical significance ( Fig. 1h ).

On the other hand, binding of rEgAgB8/2 to macrophages was not observed; the binding index showed a trend to increase in a dose dependent manner, but this trend did not reach statistical significance (Fig. 4a ).

The capsular repair showed a trend toward increasing anteroinferior translational stability compared to the Latarjet procedure, but this did not reach statistical significance.

In WT mice injected with LpX ( Fig 5A ), a small trend toward increasing UACR values was observed but did not reach statistical significance ( P = 0.106, One Way ANOVA).

ADC values of these regions showed a positive trend, but did not reach statistical significance.

Notably, Pdgfd -/- mice showed a trend towards smaller islets, although the differences did not reach statistical significance (p = 0.21) due to large standard deviations ( Fig 7J ).

There was also an overall trend toward decreasing the number of steps in the knot-tying process when comparing the original stimuli to the knots demonstrated by the last participant, though this did not reach statistical significance.

Secondly, the sample size, particularly for subgroup analyses, limits statistical power and may explain why some findings, such as the borderline significance of steroid use, did not reach statistical significance.

Similarly, there was an observed trend indicating that patients with PA with posttreatment PRA levels between 1 and 2 ng/mL per hour had a lower incidence of MACE compared with those with PRA levels either <1 ng/mL per hour or >2 ng/mL per hour; however, this trend also did not reach statistical significance.

Comparing the diameter of unruptured to ruptured aneurysms, we found a slight trend that did not reach statistical significance towards a greater diameter in the unruptured group compared to the ruptured group.

Although the fresh-to-dry ratio displayed a negative trend, it did not reach statistical significance, indicating that dry matter accumulation efficiency is governed by other regulatory pathways.

A decreasing trend was also observed when comparing to the Ctrl_AD group, although the difference did not reach statistical significance (Fig. 1 L).

The results of the ELISA did not reach statistical significance, perhaps because of fewer replications and high individual variation, but it showed a decreasing trend.

For the other-oriented Justice Sensitivity Index (JSI), acute lorazepam administration showed a trend toward reducing overall other-oriented JSI scores, although this effect did not reach statistical significance [t(80) = -1.943, p = 0.056].

Medullary pyramid thickness showed a trend toward decreasing renal length (0.625 ± 0.355 mm) but this measurement did not reach statistical significance ( p = 0.08).

Similarly, gene expression of the early adipogenic marker PPAR - γ showed a trend toward greater expression at day 7 in cells derived from SAL, however this did not reach statistical significance ( p = 0.06).

The accumulated concentration of exhaled CO showed an increasing trend with increasing ribavirin treatment dosage, though the group differences did not reach statistical significance.

The sperm count in Magea -null epididymis was slightly lower than that of wild-type controls and showed a decreasing trend, although the data did not reach statistical significance ( Supplementary Fig.

Although the combined effect of the Karnofsky Index and COVID-19 severity on survival showed a trend toward association, it did not reach statistical significance.