Barely Significant
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“did not reach statistical significance”

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In the literature

As said before, in the pineal gland ( Supplementary Table S4J ) phototransduction was also a highly significant pathway ( q- value = 0.006) while in the remaining brain regions it did not reach statistical significance. 3.5 Analysis of differential gene expression in pregnant and non-pregnant goats Samples from the pineal gland were not included in the differential expression analysis, since the removal of an outlier sample decreased the number of replicates from the pregnant group to two, which is insufficient to make a sound statistical analysis.
The medium effect sizes indicate that although the study may have been underpowered due to a small sample and therefore did not reach statistical significance, there is an effect of medium importance in the cognitive areas of selective attention and language that may be significant in larger, more heterogeneous samples.
Other class I HLA alleles and class II alleles HLA-B*08:01, B*40:02, DRB1*04: 01, DRB1*04: 05, DRB1*14: 01 and DRB1*16: 02 also had a clear trend of greater frequency, while DRB1*15:01 of lower frequency, but did not reach statistical significance after Bonferroni’s correction, probably because of the small sample size.
In initial analyses of the exploratory cognitive endpoint in the phase 2 EMERGENT-1 study, KarXT showed a trend towards greater improvement in cognitive performance relative to placebo over the course of 5 weeks of treatment but did not reach statistical significance.
An overall trend toward an increase in BMI was observed at the long-term follow-up that however did not reach statistical significance due the small sample size, but in the majority of participants BMI changes were stable or improving over time [ 80 , 81 ].
However, several non-significant HRs with a low 95% confidence interval and a statistical trend point to the direction, strength, and precision a variable might predict in this explorative analysis: Stress experience : After selecting only married or patients with a partner, this follow-up found that marital stress was included in a significant model but did not reach statistical significance.