“did not reach statistical significance”

In this study the unmodified TrkB agonist antibody showed a trend towards limited neuroprotection in the SNc, although it did not reach statistical significance, despite a 3-fold greater potency relative to TXB4-TrkB.

HAR showed a trend toward increased DANE risk, although it did not reach statistical significance (OR, 1.59, 95% CI, 0.86-2.96, P = .140).

Although participants with sarcopenia also showed a trend toward an increased risk of CVD compared to those without sarcopenia, this finding did not reach statistical significance (HR 1.01, 95% CI 0.81–1.26).

Although the combined status of TFAM upregulation and TRAF2 downregulation showed a trend toward improved survival, this did not reach statistical significance, likely due to limited sample size ( Figure 7 F).

A decreasing trend was noticeable in the TFBP treated groups in relation to this measure, but did not reach statistical significance (Fig. 6 A, B).

Although an increased age, particularly beyond 51 years, showed a trend toward reduced engagement in PA in our study population, it did not reach statistical significance.

As shown in Figures 6d and 6e , lysosomes from nfe2l2 -KO mice showed a trend toward reduced RNASE uptake in comparison with Nfe2l2 -WT littermates, although it did not reach statistical significance.

Brain AD60129 displayed a positive trend in terms of amyloid deposition compared to controls, although this increase did not reach statistical significance.

While the reduction in serum triacylglycerol was considered practically significant, the influence of buttermilk consumption on serum apoB100 levels did not reach statistical significance ( 99 ).

19 Although the improvements in TEWL (transepidermal water loss) and SCH (skin corneum hydration) did not reach statistical significance, a positive trend was observed in the alleviation of subjective symptoms assessed through the SS-10 questionnaire.

For bloating, probiotics demonstrated a small trend toward improvement (SMD 0.158; 95% CI: −0.107 to 0.422), although this did not reach statistical significance.

In initial analyses of the exploratory cognitive endpoint in the phase 2 EMERGENT-1 study, KarXT showed a trend towards greater improvement in cognitive performance relative to placebo over the course of 5 weeks of treatment but did not reach statistical significance.

Although HMGB1 did not reach statistical significance, it still showed a clear trend that higher expression indicated a worse prognosis (Supplementary Figs. 9 and 10 ).

Although this increase did not reach statistical significance, it demonstrated a positive trend toward improved target attainment.

Overall, survival analyses showed a trend toward better OS for HPV-positive (67% survival) compared to HPV-negative (27% survival) patients but that did not reach statistical significance ( p = 0.12), most probably due to the small number of HPV-positive cases ( Figure 4 A). 2.3. p16Ink4a Protein Immunohistochemical (IHC) Staining In view of the small number of HPV-positive HNSCC patients found in this cohort, and the limited amount of pathological materials available, a subset of 50 representative specimens were processed for p16 protein IHC staining.

In our study, the OMT group demonstrated significant reductions in the CA index, indicating an improvement in cervical alignment, and although the LA index showed a trend of reduction, this did not reach statistical significance, however.

mRNA Expressions of Human Nucleus Pulposus Cells Treated With C/G/GP Hydrogel Containing LVS‐NPs After 24 h of treatment, the human nucleus pulposus cells treated with 5 μM lovastatin (group L) showed a trend toward higher mRNA expression of ACAN , DCN , and SOX9 compared with the other groups, although the difference did not reach statistical significance ( p ‐value = 0.081, 0.070, and 0.092, respectively; Figure 5A ).

Statistical analysis revealed a significant difference between the combined model and MP2RAGE-only model (p = 0.035), while the difference between the FLAWS-only model and MP2RAGE-only model showed a trend but did not reach statistical significance (p = 0.124).

For TNF-α and IL-17, although CM treatment showed a trend toward reduction, the differences between the model and CM groups did not reach statistical significance ( p > 0.05).

Analysis of β cell area in Ucn3-Cre;Robo1 Δ/Δ , 2 flx/flx islets showed a trend towards larger β cell area in the Robo KO when compared to controls though this did not reach statistical significance, further pointing against β cell death in Robo KO mice as an explanation for the islet architectural defects (Fig. 5B ).

sOPN showed a trend toward higher levels in advanced disease but did not reach statistical significance.

Food intake in the model group was significantly lower than that in the control group on days 14 and 21 ( p < 0.05), while the domperidone group showed a trend toward increased food intake compared with the model group, although the differences did not reach statistical significance at some time points. 2.2.

This showed a numerical trend favoring panitumumab that did not reach statistical significance [ 6 ].

However, when adjusted for multiple clinical covariates in the multivariate model, the association between baseline TEC and achieving EASI 75 was attenuated and did not reach statistical significance ( P = 0.158), although a positive trend was maintained.

The likelihood of discussing menstrual issues with healthcare workers showed a positive trend toward better knowledge, though this association approached but did not reach statistical significance (OR = 1.7, 95% CI: 0.9–3.1, p = 0.065).