“did not reach statistical significance”

Of note, heterozygous Pot1a +/L261S mice also showed a trend to have shorter telomeres compared with wild-type mice, though the difference did not reach statistical significance ( Fig. 1 G).

Although the MDF difference between conditions at the mid-point did not reach statistical significance, the effect approached the threshold ( p = 0.055), suggesting a possible trend.

Descriptive data showed that treatment-naïve patients receiving RTX experienced no glucocorticoid-related adverse events, whereas relapsed patients exhibiteda statistically significant reduction in steroid dosage and a decreasing trend in relapse frequency after RTX, although the latter did not reach statistical significance.

The NF1 -deficient clones N0(5) and N0(32) showed a slight trend toward faster growth over the course of a 3-day assay, but this did not reach statistical significance.

≥12 months) showed a trend toward association with OS, although this did not reach statistical significance [HR: 0.63 (95% CI: 0.33-1.21); p = 0.16], as shown in Figure S1A-D (see online supplementary material for a color version of this figure).

Although these changes did not reach statistical significance, they indicated a positive trend in plasma total cholesterol, LDL, and non-HDL cholesterol concentration, particularly in the VG and EAT groups compared to CTRL group.

Although these correlations were moderate, the results did not reach statistical significance, indicating that higher health spending does not necessarily translate into greater alignment with international standards, nor does it imply a clear trend toward the inclusion of medicines not contemplated by the WHO.

Although screening ALP levels showed a trend toward elevation in osteopenic infants, the difference did not reach statistical significance.

While both mMRC score ≥2 and radiological progression showed a trend toward increased mortality risk, these associations did not reach statistical significance as shown in Table 4 .

Vimentin expression showed a trend toward increased levels in the mucosa of mock‐treated progeroid mice, though this did not reach statistical significance (Figure S6A,B ). α‐SMA staining revealed no evidence of myofibroblast activation, indicating an early fibrotic stage (Figure S6A ). qPCR analysis of plasminogen activator inhibitor‐1 (Pai‐1) and Tgfb1 in total colonic extracts indicated a trend toward increased expression in mock Lmna G609G/G609G mice, though these differences did not reach statistical significance (Figure 3D ).

Although the odds ratio was below 1, suggesting a possible trend, this association did not reach statistical significance.

Confirming the latter observation, we detected significant higher frequencies of Cd11b + Ly6G – Lys6C + monocytes in the livers of Tgr5 −/− compared to WT littermates ( Figures 2 E and S2 A), while frequencies of neutrophils (Cd11b + Ly6G + Lys6C − ) in the livers of Tgr5 −/− mice showed a trend toward upregulation but did not reach statistical significance ( Figure S2 B).

While differences between medication classes did not reach statistical significance, GLP-1 RAs showed a trend toward greater efficacy at 18 and 24 months[ 95 ].

Although reductions in total serum IgE did not reach statistical significance, XG + CWMT showed a favorable trend, suggesting potential immunomodulatory effects.

A negative trend was observed between Afamin levels and estimated glomerular filtration rate (eGFR), although it did not reach statistical significance.

Although it did not reach statistical significance, the incidence of perioperative MIs showed a trend toward less MI rate in the Mini-Bypass group.

In contrast, among patients without MPR, adjuvant therapy showed a trend toward better DFS, although this did not reach statistical significance ( p = 0.188).

Craniocaudal tumor dimension ≥ 40 mm showed a trend toward association with FFR but did not reach statistical significance after adjustment (HR = 2.02, 95% CI = 0.91–4.49, p = 0.084).

This suggests a positive trend toward improved outcomes with EMD, though the effect did not reach statistical significance at the pooled level.

Although the distance traveled in the central zone, time spent in the center, and wall-standing time in the EA-stimulated groups did not reach statistical significance compared with the model group ( p > 0.05), these parameters consistently showed a trend toward improvement ( Figure 2 E–G).

Notably, while allergic comorbidity (OR = 0.46; p = 0.070) showed a trend, it did not reach statistical significance.

Although the θ and α effects during the N1 window did not reach statistical significance, both bands showed a trend toward increased modulation.

Furthermore, although the improvement in PA did not reach statistical significance, a positive trend was noted, which may reflect improvements in cellular membrane integrity and overall nutritional status.

In Duan et al.’s study, while a decreasing trend in heart rate was observed in the SGB-L group, this change did not reach statistical significance.

Thoracic consolidation radiotherapy (TRT) showed a trend toward an OS benefit compared to systemic therapy alone, although this did not reach statistical significance (P = 0.073; Supplementary Figure S2 ).