“did not reach statistical significance”

Age >66 years (HR: 1.46; 95% CI: 0.98–2.18; p = 0.061) and an Eastern Cooperative Oncology Group (ECOG) score of 2 (HR: 4.0; 95% CI: 0.95–16.84; p = 0.059) showed a trend towards an association with shorter PFS but did not reach statistical significance.

In adjusted models, severe wasting (OR, 1.64 [95% CI, 0.83–3.25]; P =0.16) and moderate wasting (OR, 1.35 [95% CI, 0.81–2.24]; P =0.25) showed a trend toward increased major infection but did not reach statistical significance.

Although in some models there was a clear trend in the decrease of IFNAR1 expression in M-MDSC as compared to Mon, it did not reach statistical significance (Fig. 1c ).

Although MDTM showed a trend toward an improved survival rate among patients with stage IV HNC, it did not reach statistical significance [combined HR = 0.81, 95% CI (0.59–1.10), Z = 1.35, P = 0.18, Figure 3 ].

Second, DKP/TRAM showed a positive trend over placebo in terms of first achieving an NRS-PI score < 4 or a pain intensity reduction ≥ 30% from drug intake up to 8 h after the first dose, but the difference did not reach statistical significance.

NP-led MET calls showed a trend toward decreased mortality within 24 h of index MET call, but this did not reach statistical significance (3.4% vs. 7.2%, 0.47 (0.21–1.05); p = 0.06).

Although there were numeric differences in NNH values, these differences did not reach statistical significance, with the exception of a marginal significance for 240 mg galcanezumab (indicating fewer adverse events than placebo) and onabotulinumtoxinA (oBTA, indicating more adverse events than placebo).

There was a strong trend, which however, did not reach statistical significance, towards a higher expression of DRD2 in GBM1 (70 (80–40)) than in the HCs (45 (54–40)).

In silico analysis of the Cancer Genome Atlas (TCGA) data including 412 chemotherapy-naive, invasive, high-grade urothelial tumors [ 3 ] using the Human Protein Atlas platform ( http://www.proteinatlas.org , accessed on 6 March 2021) showed a trend towards longer survival in UCB with high expression of GRHL3; however, it did not reach statistical significance ( Supplementary Figure S6 ) [ 24 ].

Although the larger tumor size showed a trend towards an increased risk of residual dysplasia, it did not reach statistical significance ( Table 2 ).

While we found there was a clear trend in PDGFR‐β immunoreactivity in the order: old controls >PSND > PSD (Figure 5 A), the mean values for PDGFR‐β assessed by ELISA did not reach statistical significance ( P > 0.05).

While the 1 mg/L and 100 mg/L groups showed an increasing trend but did not reach statistical significance, the gata4 transcription levels peaked in the 10 mg/L groups, showing a 1.91-fold increase over the control group ( Figure 4 B).

Although there was a positive trend between higher accumulation and higher silencing efficacy, the observed correlation did not reach statistical significance.

While the secondary endpoints did not reach statistical significance, but showed a positive trend in favor of the ER2EP pathway ( Figure 2 ).

Consistent with the sequencing results, compared with non‐AF patients, two tsRNAs (tsRNA‐5006c‐LysCTT and tsRNA‐5030c‐GluCTC) were significantly upregulated in AF patients, and the remaining one showed an increasing trend but did not reach statistical significance.

The authors reported an overall trend towards less intraoperative transfusion requirements in patients supported with ECMO than in patients supported with CPB, but the difference did not reach statistical significance.

26 - 28 There was an increasing trend in cervical lordosis in patients who underwent 2-level CDR, but the differences did not reach statistical significance, probably because of the limited sample size.

Eyes injected with Das-PLGA showed a trend for reduced expression of aSMA but the difference did not reach statistical significance (Table 2 ).

For functional mobility, although there was a favorable trend in improvement, such improvement did not reach statistical significance.

Although the chlorophyll a/chlorophyll b ratio in colonized leaves showed a decreasing trend compared with the control, it did not reach statistical significance.

Postoperative hypoparathyroidism on the first day (POD-1) showed a trend toward reduction in the ICGA group (25.8%) compared to the control group (35.8%), although this did not reach statistical significance ( p = 0.09).

Patients with CRC in group 2 showed a trend towards a better overall survival with low to intermediate PCI values (<17), but did not reach statistical significance ( p = 0.183).

Although it did not reach statistical significance, the incidence of perioperative MIs showed a trend toward less MI rate in the Mini-Bypass group.

While treatment with emollient therapy showed a trend toward increased weight gain, especially in the younger patients (2 to < 6-months old), this effect did not reach statistical significance and time to clinical recovery from the acute phase of illness was not measurably impacted.

LV systolic function index (+dp/dt) showed a trend toward improvement but did not reach statistical significance ( P >.05).