Excerpts

The GLMs suggest that precipitation negatively affected the GF intensity of each forest significantly affected in two GF events, S02 and S10 ( Table 1 ) with almost significant estimate shown for S05.

The relationship approached significance (p value of 0.0503) for VF 1-5 .

At 17.5 dpc Noggin −/− myofibers were slightly but significantly thinner and this trend persisted until 18.5 dpc where the difference was apparent ( Fig. 1 F–H’).

Furthermore, the ambient temperature has increased by 1 °C over the past 50 years and precipitation shows a significant increasing trend in the 1980s and 1990s, and the average annual precipitation shows an increasing trend with a magnitude of 6.8 mm per decade 37 , while warming has decreased soil moisture content and enhanced the potential for oxidation of CH 4 38 .

Additionally all mutants showed a trend toward steeper slopes than WT, but only the augmentation slope in dlgA mutants reached statistical significance ( Fig. 5 D).

having “ikigai” and decisiveness, had a nominally significant association with breast cancer incidence 12 .

This conservative selection of a threshold ensures that the scores are well above the level of random values, and that only highly significant interactions are retained.

In support of COX11 and TOM1L1 being the targets of this breast cancer susceptibility locus, eQTL analyses in normal breast tissue showed borderline significant associations of the risk alleles of top candidate causal SNP rs2787486 with increased expression levels of both TOM1L1 and COX11 ; candidate SNP rs2787481 also showed evidence of allelic imbalance in COX11 expression.

3c ) we can observe an increasing trend with particle radius, the optical retardance ( Fig. 3d ) does not appear to change in the range of particle size investigated.

In addition, because of the heterogeneity of the sediment, the settling of the SPM-MWCNT may be very complex and does not have an evident trend across the pH range, as was shown in Fig. 5d .

Not surprisingly, in the case of natural background, the correlation between Pixel and human RDMs are very low and almost insignificant at all levels ( Fig. 12 dashed dark purple line copied on all panels).

There was a significant trend over the quartiles and a compelling gradient of increased prevalence of cognitive impairment for levels of Lp-PLA 2 .

In both the case of ABT-263 and cisplatin, we observed highly heterogeneous responses to the drug treatments, illustrating the need for population level analyses as completed here when analyzing the effects of drugs on mitochondrial morphology, as such heterogeneity may be significant in determining overall tumor response to treatment.

Further, ERα in TS was the only marker that served as an independent prognostic factor for PCD (HR: 0.28, 95% CI: 0.1–0.78, p = 0.015) along with Gleason grade ≥ 9 and PNI, although aromatase in TE tended towards significance.

The changes in CD68+ macrophages and Ki-67+ cells showed an increasing trend going from uninfected to SIVnoE to SIVE animals, but were only significant for CD68+ macrophages between uninfected and SIVE animals; however, compared to both uninfected and SIVnoE animals, the number of CD68+Ki-67+ cells in SIVE animals was significantly higher, indicating an increase in Ki-67+ macrophages in SIVE.

Highly significant reductions in 12 phosphatidylcholines and significant changes in an additional 57 metabolites classified as amino acids, biogenic amines, acylcarnitines, glycerophospholipids and sphingolipids were observed in the PH compared to the control group.

The reconstruction shows a significant warming trend with a rate of 0.74 ± 0.12 °C/decade for the period 1970–2000, but a decreasing trend from 2001 to 2012.

The AR(DHT) LNCaP condition showed a trend similar to AR(FL) in the CWR22Rv1 cell line ( Fig. 5C ).

Intensive research demonstrates that natural product and/or natural product structures continued to play a highly significant role in the drug discovery and development process 2 . β-carboline and its saturated analogue are common structural motifs in natural products and pharmaceuticals 3 . β-carboline alkaloids were originally isolated from Peganum harmala, which have been used as a traditional herbal drug for hundreds of years in cancer in Northwest China 4 .

C max (194.09 ± 24.85 ng/mL in PB rats versus 277.01 ± 71.22 ng/mL in rats) of atorvastatin in PB rats showed a trend to increase, although no significance was observed.

Alternatively, it was possible that the nominally significant relationships between total serum 25OHD and either BMD or bone metabolism markers might largely be ascribed to some unidentified confounding factors in the observational analyses.

In summary, a decreasing trend of gastroschisis prevalence was observed in Liaoning Province over the last 10 year which was the most recent and detailed evidence for time trends in the prevalence of gastroschisis in China.

Notably, borderline significant decreasing trend was observed in Dandong, with APC of −8.42% (95%CI: −16.69 to −0.66).

In addition to the distribution of energy to the two outputs in a fan-out circuit, we also observe an interesting trend in the sum of energy transferred to the two outputs and its relation to the stray field antivortex dynamics.

Interestingly, we found that among all tissues examined, the breast mammary tissue showed the strongest statistical evidence for non-random connectedness among breast cancer genes (p = 0.0015), and this result was nearly significant after Bonferroni correction (p corrected = 0.07).