s-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY issue-copyright-statement © The Author(s) 2020 Introduction According to the World Health Organization report, the number of patients with esophageal squamous cell carcinoma (ESCC) is on an increasing trend; it is considered to be the sixth most common types of cancer in men and the thirteenth most common types of cancer in women 1 .
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showed only a nonsignificant trend of increase in ICD shocks.
a clear trendgold
5G , p = 0.08), albeit a clear trend was still detectable.
a positive trendgold
Moreover, a positive trend with increasing birth length was noted for premenopausal breast cancer.
We further noted a statistical trend of borderline significance for a greater risk of premenopausal breast cancer in daughters with increasing birth length (p for trend = 0.06; Table 4 ).
a negative trendgold
Supplementary Figure S5, E shows that for all experimental conditions in these studies, the regression coefficient showed a value of −0.2847, indicative of a negative trend, but not a strong linear relationship.
a strong trendgold
This was strongest in the control and cells exposed to 100 μM glutamate, but still indicative of only a weak rather than a strong trend.
In multi-adjusted models, δ 15 N was still negatively associated with the risk of being severely stunted whereas the association was marginally significant for δ 13 C (Supplementary Table S4 ).
In contrast, BPF99 had a highly significant effect on JNK and p38 MAPK phosphorylation returning them to levels seen in chow fed mice and lower than the levels seen in positive controls (Fig. 5 , panels A, D and E; p < 0.001 for both).
It significantly improved NASH resolution (p < 0.001) and the SAF scores (p < 0.05) while the NAS improvement approached significance.
The analysis of the available historical data 77 highlights a significant trend of acidification of the water masses in the marine area from which the organisms were sampled (Supplementary Fig.
Figure 7B indicates that miR-135b inhibition consistently showed a trend of lowering the expression level of the Wnt target genes compared to a control transfection although without reaching statistical significance.
Analyses were carried out using Graphpad Prism 7 (GraphPad Software Inc., San Diego, CA, USA), with P values < 0.05 considered statistically significant and P values < 0.01 considered highly significant, respectively.
We determined levels of IL-8 and CRP in plasma among HSCT patients and found a marginally significant overall correlation between the CRP and IL-8 levels.
A marginally significant positive association between MSPSS scores and rsFC was also observed between the right amygdala and bilateral precuneus ( x = 6, y = −60, z = 51; T (45) = 4.12; 648 mm 3 ; BA 7; p < 0.10, cluster-level corrected).
The TC adsorption capacity of ceramsite showed a trend of firstly increasing and then decreasing with the increase of preheating time (Fig. 4 ).
In modern nautilids with and without pathology, chamber volumes show an increasing trend although individuals with a pathology leading to premature death often exhibit fluctuations.
Highly significant heterogeneity was observed in both the χ 2 and I 2 tests, hence the implication that all studies evaluate the same effect was decisively rejected.
Runoff variation trend Figure 2 shows the temporal runoff variations of river basins seleted from 1981 to 2014 based on SWAT simulations The runoff of the four river basins shows a decreasing trend over the 34 year period. the runoff reduction of Dadu River and Tuojiang River basins were relatively substantial, with gradients of −1.93 mm/a (R 2 = 0.17) and −1.90 mm/a (R 2 = 0.12), respectively, while the reduction of Qingyi River and Minjiang River basins was relatively less, which gradients −1.04 mm/a (R 2 = 0.09) and −1.16 mm/a (R 2 = 0.11), respectively.
It showed an increasing trend before 1998 and a decreasing trend after 1998, confirming the weakening of the MH intensity during the GWH period (Fig. 5a ).
a positive trendgold
Similar to SST, upper ocean heat content (0–200 m) and sea level anomaly show a positive trend during the GWH period (Fig. 2b ) confirming the warming of the upper water column during the period.
a negative trendgold
SST anomaly in the MH region shows a negative trend during the preGWH and positive trend during the GWH (Fig. 2a ; red line).
The lack of a significant trend in rainfall was mainly due to Indian monsoon is a complex nonlinear phenomenon involving atmosphere, ocean, and land-based processes 34 .
However, our results did not show a decreasing trend in 20 years’ time period for any studied nutrients in the CR-LTE plots.
pyright-statement © The Author(s) 2020 Introduction According to the European Centre for Disease, Prevention and Control (ECDC), migrants in the European Union/European Economic Area (EU/EEA) have a higher risk of HIV infection and related co-infections, such as HBV, HCV and tuberculosis (TB), with an increasing trend in populations from Latin America and East Europe, and a decreasing one in populations from sub-Saharan Africa, although they still represent half of diagnosed individuals 1 , 2 .