Excerpts

pyright-statement © The Author(s) 2020 Introduction According to the European Centre for Disease, Prevention and Control (ECDC), migrants in the European Union/European Economic Area (EU/EEA) have a higher risk of HIV infection and related co-infections, such as HBV, HCV and tuberculosis (TB), with an increasing trend in populations from Latin America and East Europe, and a decreasing one in populations from sub-Saharan Africa, although they still represent half of diagnosed individuals 1 , 2 .

We found that Rhbdf2 −/− mice had a significant bone phenotype; in line with our GWAS data, Rhbdf2 −/− mice displayed a highly significant increase in BV/TV and Tb.N (Fig. 6 ).

Since 1980, the northern region has experienced a warming trend of 0.07 to 0.11 °C yr −1 , whereas the more southern region experienced a warming of 0.01 to 0.07 °C yr −1 ; with four stations showing a significant trend at <0.1 level (Table S1 ).

Conclusions The characterization of a marker associated with lignotuber development is highly significant for Eucalyptus as individuals that have this organ can regenerate quickly after coppicing or fire.

IOP elevation in Brown Norway rats showed a trend towards decreased expression of ATP5H.

On the other hand, an increasing trend in the expression of FOXO1 (31%) and Map3K11 (179%) genes and a decreasing trend in the expression of Cox17 (17%) and G6PD (15%) genes were observed in ET-1 treated RGCs (Fig. 4 ).

When stratified by age (<65 and ≥65), all blood cell counts remained significantly associated with mLOY at similar magnitude except for lymphocyte counts which were only marginally significant in the ≥65-year-old group (Tables S16 – S19 ).

While we couldn’t demonstrate a significant difference regarding the VEGF-A165b to VEGF-A ratio, we found a statistically highly significant difference between breast cancer patients and control group.

There is a slight trend of the densities decreasing and thickness values increasing as oxygen deposition pressure increases for the films grown at same deposition conditions (see Fig.

In general, Ad4-prM-E vaccination induces lower, but still highly significant, levels of T cell immunity as compared to Ad5-prM-E vaccination 33 .

A p < 0.05 was considered to be significant (denoted by *), and a p < 0.01 was considered as highly significant (denoted by **).

Our data showed a trend of reduction in biofilm formation in all isolates treated with 60 and 100 μg/ml of FGE in the presence and absence of 3% FBS as measured by the XTT assay.

1a , there was an increasing trend in extraction yield of LAHP from 40 °C to 100 °C, which was in agreement with other reports on polysaccharides extracting 23 , 30 .

The accumulation of microplastics modelled in the present study could show that even when other uptake routes are not considered, and assuming that only 0.01% to 1% of very small particles are regularly translocated, the number of accumulated microplastics might be significant in fishes with a long lifespan, up to 200 particles over 15 years in the modelled cod.

Thus, we felt that the non-correction t-test still provides information on the trajectory of some leads that were close to being significant and still provides value to the reader.

At the highest POS concentration tested (5%), there were a decreasing trend or no change in overall for the THRB counts.

For each data set, we examined whether scaled connectivity (a metric of whether a gene is acting as a “hub”) correlated with the depth of literature base using Kendall rank correlation; in the PRAD dataset, the correlation was miniscule, negative, and barely statistically significant; in the COAD data set, the correlation was miniscule, positive, and statistically significant, and the correlation was insignificant in the GBMLGG dataset (Fig. 2a–c ).

Finally, there were insufficient structural recurrences and cancer-specific deaths in the short follow-up period, and whether there was a significant difference in prognosis between male and female PTC patients is still uncertain, although a nearly significant difference was demonstrated during this short follow-up.

Animal and cohort study both showed that amiodarone could increase serum digoxin level, digoxin bioavailability, and showed a trend to prolong digoxin elimination half-life and decreased its renal clearance 23 – 26 .

Knowledge of surfactant micelle behavior on a biological system is extremely significant as the binding of naturally occurring substrates or added surfactant micelle may affect the biological process.

While not significant, a clear trend in muscle activity was visible for known perturbation timing (Fig. 6 ).

Table 2 shows that the contribution rate of evapotranspiration to water resources revealed an increasing trend and, conversely, the contribution rate of precipitation revealed a decreasing trend, which indicated that evapotranspiration was gradually replacing precipitation as it pertains to the contribution rate to local water supply, and that evapotranspiration was the main cause for local droughts.

An increasing trend in monthly temperature and rainfall was observed from January until July and June, respectively.

An overall trend is thus difficult to discern, and is not actually expected as biodynamic preparations are thought to balance yields 65 .

The highly significant structural templates used in the modeling of the IDD protein domain through I-TASSER are listed in Table 1 .