Excerpts

Moreover, there was a positive trend for the association across increasing HDL-C quartiles and POF, PNec and mortality after multivariable analysis (p values were <0.001, <0.001 and 0.043, respectively).

Only Hequ and Xingxian stations exhibited decreasing trends in February, and only Suide exhibited a decreasing trend in June.

Winter precipitation at most stations in the study area displayed an increasing trend and most stations exhibited decreasing trends in the spring, summer autumn.

Finally, in subgroup analysis, pATR expression and the pATR/pChk2 co-expression model were associated with an increased risk of death within a 10-year timeframe in the subgroup of patients with elevated Ki-67 levels and with node-positive disease (Supplementary Figure 1 ), although to a borderline significant extent.

All conditions showed a trend in which vasodilation in response to 1 μM acetylcholine over four weeks increased with perfusion time (Fig. 2C ).

The differential pattern is again extremely significant as indicated by p values in Table 2 .

In Japanese cedar and hinoki cypress, the 137 Cs concentration in wood showed an increasing trend in half of the plots.

However, after intervention, trend test was highly significant (P-trend < 0·0001), showing > 51% of subjects with Fok-I TC genotype and almost all subjects with CC genotype remained vitamin D deficient (Table 2 ).

However, the ratio of water consumption of three plain reservoirs in total water consumption showed a decreasing trend (Fig.

Results suggest that climate and landscape elasticity showed an increasing trend with the increase of aridity index.

Although our results showed a trend of increasing antioxidant capacity, the significantly decreased oxidative stress may suggest the possibility of the reduced occurrence of oxidative damage, which may partially contribute to improving functional and health-related outcomes.

From Table 1 , it is obvious that C 4 shows an increasing trend (+0.003% yr −1 ), whereas those of C 5 –C 12 diacids (particularly, C 5 , C 7 , C 8 , C 9 , and C 12 ) show significant (p < 0.05) decreasing trends during the study period.

The APRI, FIB-4, RPR and GPR showed an increasing trend with fibrosis stages in CHB patients.

Moreover, when promoter occupancy of Pol I and UBF was compared between PGC-1α competent wild-type and PGC-1α knock-out tissue, we found a highly significant difference of Pol I and UBF binding to the rDNA promoter after precipitating the same amount of protein (Fig. 3b ).

In fact, at the highest dose of 10 μM, RGFP966 exposure resulted in a slight trend of decrease in neurite length (Fig. 5a ).

The values of the maximum quantum yield of photosystem II ( F v / F m ), the effective photochemical quantum yield of PSII (ΦPSII), and the photochemical quenching ( qP ) showed a decreasing trend related to NaCl concentration and treatment duration (Fig. 1A–C ).

Consistently, no additional significant increase in LC3-II was observed in the CQ plus ZAS-treated group compared to the ZAS only-treated group, as determined by the western blot assay, although an increasing trend was observed at 4 h (Fig. 4C,D ).

This suggests a similar endocytic membrane trafficking defect. Using the Rab5 endosomal marker in quantified comparisons, both dfmr1 null mutants (0.1 ± 0.03 μm 2 , n = 23 boutons, p < 0.001) and PN-targeted shrub OE GOF (0.04 ± 0.01 μm 2 , n = 29, p < 0.01) show highly significant increases in the number of endosomes per synaptic bouton area compared to controls (Fig. 3C ).

Using the regression coefficients of the 9 nominally significant (α = 0.05) SNPs (rs885479, rs1805008, rs1805007, rs28777, rs12896399, rs1042602, rs1393350, rs12821256, rs12203592; see Supplementary Table S2 , available) as weights, we calculated a polygenic score in the cortisol/cortisone sample according to β 1 *rs885479 + ... + β 9 * rs12203592.

A SWISS-MODEL analysis revealed that the class A carbapenemase KPC-2 in the database has a three-dimensional (3D) structure matching that of PAD-1(GQME value 0.67, QMEAN value −1.61), which is highly significant in carbapenem resistance, especially in clinical Enterobacteriaceae isolates 11 .

As observed before for P-dopants 35 there is a clear trend for larger NCs to incorporate more B-atoms, as indicated by the linear fit (dashed line).

Although no group differed significantly in the adjusted regression models, a marginal significance was observed among seventh-grade boys.

From 1988 to 2008, there was an increasing trend of hypertension prevalence in Americans aged 40 years and older 11 , however, the prevalence of hypertension in Japan 13 , Germany 14 , Italy 16 and Korea 17 decreased.

It is worth noting that some beneficial microbes, such as Arthrobacter and Chaetomium , presented an increasing trend in ATS soils in Muping, Laizhou, and Huludao.

4b ), with the exceptions of single species showing marginally significant correlation with specific signals (Supplementary Table S2 ), as in the case of Ganoderma (122–126 and 151–153 ppm), Trichoderma (3–24 and 132–138 ppm) and Umbelopsis and Mucor (95–105 ppm).