Excerpts

37 also observed a decreasing trend in μ s ’(λ) (p = 0.16) in high-grade neoplasia using spectroscopy.

Additionally, Taqman RT-qPCR analysis showed a trend for an increased expression of the Complement Component 3 (C3 ) gene, concordant with the RNA-Seq dataset (fc = 3.57, P = 0.162; Supplementary Fig.

Both S group and P group showed a trend for increased NR1 expression (AVOVA, p = 0.17).

On stratifying by weight status, the association of PC2-Z with serum TG and GGT was nominally significant, and remained close to significance after FDR correction in all groups ( P < 0.17), except for underweight children (Supplemental Table 6 ).

1c ), we observed a positive trend of increase in AA with decreasing SES (β = 0.78, 95% CI: −0.33, 1.89; p = 0.17, comparing the extreme categories: stable unskilled and stable professional), with some attenuation after further adjustment for NCD risk factors (Table 6 , Fig. 1d , β = 0.77; 95% CI: −0.37, 1.92; p = 0.19), although these associations did not reach statistical significance.

We observed significant increase in DPT cell absolute numbers (cisplatin 231.8 ± 51.72 vs control 92.50 ± 35.44, P ≤ 0.01) and an increasing trend in the percentage (cisplatin 0.40 ± 0.14% vs control 0.16 ± 0.03%, P = 0.17) in cisplatin treated mice compared to vehicle control mice at 72 h (Fig. 6 A).

The KUS121-treated and control groups showed marginally significant differences in terms of a-wave amplitude (157.6 ± 72.5 μV vs. 119.3 ± 34.4 μV, P = 0.170; Fig. 3b ).

4F ), while CD8+ staining showed significant increases with S-7 ( p = 0.0312) and a strong trend towards increase with Serp-1 ( p = 0.1734) treatment (Fig. 4G ).

However, in the case of flexural modulus, all the ratios were highly significant, except for 5% ( p = 0.175) and 25% ( p = 0.275), indicating that no statistically significant difference was found between these ratios and the control.

In multivariable Cox analysis, admission BT < 36 °C showed a trend at 30 days (Adjusted HR: 1.87; p = 0.176; 22 events) and became a significant independent predictor at 180 days (Adjusted HR: 2.30; p = 0.039; 34 events).

Though not statistically significant, activated CD8 T-cells also showed a trend towards increased infiltration (p = 0.1799).

There was an increasing trend in 6MWT when training weeks increased from 7 to 12 ( P = 0.18, coefficient = 5.04, 95% CI − 2.93–13.02) and training frequency increased from 1.5 (average) to 7 times per week ( P = 0.34, coefficient = 3.30, 95% CI − 4.16–10.76) (see Supplementary Figs.

Further, there was near-marginal significance (0.05 < P < 0.18) between one CSS and mental score, both one and ≥ 2 CSSs and total scores on JHEQ, respectively.

Borderline significance (0.05 < P < 0.18) was found between one CSS and mental score, both one and ≥ 2 CSS diagnoses and total scores (mental score, one CSS, β = − 0.110, P = 0.163, ≥ 2 CSSs, β = − 0.073, P = 0.356; total score, one CSS, β = − 0.105, P = 0.177, ≥ 2 CSSs, β = − 0.122, P = 0.142).

The qRT-PCR data showed no alterations in Nfκb expression after 3 and 14 days (p > 0.05, Table 1 ), while a slight trend pointed towards an upregulation was noted at 7 days (p = 0.18, Fig. 4C ).

In contrast, although the TMA cohort showed a trend for poorer survival with PD-L1 expression (33.3% vs. 71.4%, p = 0.18), this result did not achieve statistical significance ( Fig. 4A,B ).

The group with higher hs-CRP levels (> 2 mg/L) had a higher hazard ratio for seroprevalence (HR 1.66) compared to the group with lower hs-CRP levels (HR 1.05), with the multiplicative interaction between the virus and CRP being borderline significant (p = 0.180).

The VFI showed a trend towards improvement, albeit without statistical significance in either group (enhanced: p = 0.186, standard: p = 0.813), while the magnitude of change also lacked significance ( p = 0.519).

Further analysis of the PI3K/PTEN/Akt pathway in the cyclophosphamide-treated samples showed a trend toward a decline in Akt-1 (p = 0.19) and no significant change in the expressions of Foxo3a (p = 0.8) and rpS6 (p = 0.36) (Fig. 3 D–F).

Even though the difference between normal and CRC tissue was not statistically significant, we note that there is a definite trend toward decreased CRC expression levels compared with normal tissue, with Z-scores of − 1.30 ( P = 0.19), − 1.06 ( P = 0.28), and − 1.75 ( P = 0.07) for HLA-A, B, and C alleles, respectively.

Asic2 −/− and Asic3 −/− mice showed no difference in disease progression as compared with wild-type littermates, although Asic2 −/− mice showed a trend to increased disease severity (F (1,20) = 1.778, P = 0.19) ( Fig. 1a ).

In ADV-conditioned mice, the frequency and number of CD95 + GL7 + GC B cells increased, and those of class-switched IgG1 + B cells showed a trend to increase (p = 0.19 or 0.18) when compared with those of LD-conditioned mice (Fig. 6F,G ).

Additional analyses were completed to compare the 6-min walk distance at baseline between the dropout and completed groups; findings demonstrate a statistical trend with a 35 m higher 6-min walk distance ( p = 0.196, Cohen’s d = 0.76, 95% CI − 17 to 83 m) performed by the dropout group (302 ± 84 m) compared to the completed group (269 ± 78 m) at baseline.

Although the overall KMO value was low (KMO = 0.50), reflecting limited shared variance across heterogeneous speed- and accuracy-based tasks, Bartlett’s test of sphericity was highly significant (χ 2 (105) = 14,699.82, p < 2 × 10− 1 6), supporting factorability.

Conversely, although a negative trend was observed for PM 2.5 × CO 2 in the DS proportion model ( p = 0.20), this did not reach statistical significance.