Excerpts

A multivariate model selected for the best balance of fit and complexity retained all three variables, and cluster association showed a trend towards statistical significance (HR, 1.9, CI, 0.95–3.9; p = 0.069).

In the cross-sectional part of the study mediation between trauma and retrospectively recalled premenstrual symptoms through locus of control was approaching statistical significance (association between LOC and PSST scores while trauma was controlled at a borderline significance level: p = 0.069; lower border of confidence intervals of the indirect effect starting at zero), although not reaching it.

After hybrids removing, the discriminant analysis generated also one discriminant function, with FA, D3_MC, D5_MC (marginally significant [F = 3.450, p = 0.069]) and CM3 as statistically significant variables (Λ = 0.632, χ 2 (4) = 21.073, p < 0.001).

The interaction between time regions and metrical positions was almost significant (F(2.250, 63.012) = 2.694, p = 0.069).

The differences between the groups almost reached statistical significance ( p = 0.069).

Univariate analysis demonstrated mutated NRAS to be associated with a superior LFS in the entire t(8; 21) cohort, with marginal significance ( P = 0.069).

The soluble Aβ42 levels in both AAD-66 and SI treated groups compared with the vehicle treated group showed a decreasing trend (p = 0.0692, p = 0.2451, respectively) (Fig. 3E ).

Although adult Scn2a +/− mice showed a trend towards significant slower acquisition latencies on day1–4 (two-way repeated measures ANOVA, F(1, 29) = 3.56, p = 0.0693 for genotype (borderline significance); F(5, 145) = 90.04, p < 0.0001 for day; F(5, 145) = 1.1, p = 0.3813 for genotype × day interaction), their performances were comparable to wild-type mice during the probe tests on days 5 and 12.

Stress did not significantly increase the number of spines in LAT neurons from males, though there was a strong trend (stress × distance interaction, p = 0.0696, F(29,754) = 1.425, two-way RM-ANOVA, N = 14 control, N = 14 stress).

The higher occurrence of skewed X-inactivation for co-twins of women with skewed X-inactivation was borderline significant when compared to women who had a co-twin with normal mosaics at baseline ( P = 0.07).

Fecal serotonin & improvement of psychosocial behaviour A stable level of fecal serotonin was observed in the IG while a decreasing trend was found in the CG ( p = 0.07, 249.36–220.60 pg/mg of feces) (Fig. 2 a).

Additionally, the main effect of group approached significance ( F (1,34) = 3.59, p = 0.07, η 2 = 0.07), with higher scores for the low AQ group ( M = 76.2, SD = 15.6) compared to the high AQ group ( M = 67.2, SD = 19.2).

Although statistically not significant, there was a negative trend of correlation between fecal serotonin level and Shannon diversity index of Bacteroidetes ( p = 0.07, ρ = −0.21) and Chao1 richness index of Firmicutes ( p = 0.09, ρ = −0.19), but a positive correlation with Proteobacteria richness ( p = 0.06, ρ = 0.22) (Supplementary Fig. 5 ).

However, the negative correlation of C24:0-Cer with fecal calprotectin in patients with UC was almost significant ( P = 0.07) 39 .

4 ), and a trend toward significance at 137.5 ms ( r = 0.31, p = 0.07).

Only CA2 showed a 2–5-fold up-regulation on days 7 and 28 during screening and validation with a borderline significance at day 7 (p = 0.07) and a high significance at day 28 (p < 0.0001, Table 2 , Fig. 2F ).

However, there was a trend toward significance in this group ( p = 0.07) ( Figure 2b ).

However, after adjusting for multiple comparisons (Holm–Sidak method), the relationship verged on significance (adjusted p = 0.07).

Figure 4C and D show the results for visual cortex where the correlation with binocular rivalry mean percept duration approached significance (Pearson r = 0.3, p = 0.07), whereas the correlation with spatial suppression reached conventional statistical significance (Pearson r = −0.38, p = 0.02).

Treatment of polarized ARPE-19 cells with 100 nM ZK for 3 h showed a trend (p = 0.07) to increase BECN1 expression in low autophagy-/UPR-related gene-expressing cells (Fig. 6 c) but significantly decreased BECN1, MAP1LC3B, mTOR, ATF6, DDIT3, EIF2AK3 and HSPA5 expression (Fig. 6 a,c,d,f,j,k,m) in high autophagy-/UPR-related gene-expressing cells.

Interestingly, there was only a statistical trend for total cholesterol ( p = 0.07).

Because our network analysis showed a positive trend towards significance in pathways related to growth and proliferation (EGF-pathway, PI-3K, and p53) (p = 0.07 to p = 0.09), we next tested whether MSC exosomes were able to induce cardiomyocyte proliferation.

Skin conductance responses also tended to decrease more over time in native language conditions than in foreign language conditions [Difference estimate (foreign – native): Time 1 = 0.04, Time 10 = 1.49, increase: 1.46], although the interaction between Time and Language Context only approached significance [F(1, 55.9) = 3.44, p = 0.07].

The association only approached significance for nonverbal vocalizations ( r [21] = 0.39, p = 0.07; Cook’s distance range = 0.00–0.56).

Patients in risk group 5 (M1 disease or PSA > 100 μg/l) showed a trend toward higher pro-NPY levels compared with all other risk groups combined (median 0.145 vs. 0.0965 ng/ml, p = 0.070) (Fig. 1 B).