Excerpts

Notably, NRG4 exhibited a near-significant expression difference ( p = 0.0556), supporting its potential biological relevance.

ChR2 and YFP mice did not differently extinguish responding based on press rates within the first extinction session (two-way repeated measures ANOVA, no significant effect of group or interaction, both p > 0.7132, near-significant effect of time F (3.849, 50.04) = 2.508, p = 0.0556; Fig. 3 e) or across three days of extinction (two-way repeated measures ANOVA, no significant effect of group or interaction, both p > 0.6922, significant effect of time F (1.362, 19.07) = 17.24, p = 0.0002; Fig. 3 f).

Furthermore, the Wilcoxon test showed that one-sided p values when comparing the methylation level in site 2 of TD, NTD and ND + NTD with HC group were 0.0038, 0.0252 and 0.0038, respectively; while TD also revealed borderline significance comparing with NTD (p = 0.0559).

Partial correlation also revealed a marginally significant relationship between SRS (total) T score at baseline and 12-month TTS, controlling for baseline TTS, r partial = 0.312, p = 0.056 (Spearman).

For HR and RMSSD, the interactions also remained non-significant, with the interaction between pleasantness and familiarity showing a trend towards significance for HR (β = 0.15, SE = 0.08, p = 0.056) and RMSSD (β = − 0.01, SE = 0.00, p = 0.074; all other p s’ > 0.621).

The similarity between predicted and observed standard deviations was furthermore indicated by significant correlations ( p -values < 0.035) ranging between 0.60 and 0.92, and one marginally significant correlation ( r = 0.56; p = 0.056) for BiHand trials in condition Dyn .

Interestingly, employment was a factor that had borderline significance ( p = 0.056), with prevalence being higher in the unemployed than the employed participants.

COL10A1 was also reduced after treatment, with the change in COL10A1 demonstrating a marginal trend toward significance (r = 0.29; p = 0.056) with change in height z-score over 24 weeks.

The group × target/distractors type interaction barely failed to reach significance ( F (3.16, 186.22) = 2.352, p = 0.056), but no main effect of group was found within any of the different target/distractors types ( p > 0.1, see Supplementary C ).

The interaction was marginally significant (F(3,39) = 2.75, p = .056).

For the latency, we found a marginally significant main effect of group with the HDs showing longer N170 latency than the CSs (179 ms vs. 172 ms, F = 3.95, p = 0.056, η 2 = 0.11)(Fig. 4a ).

For nanoemulsions, oil type showed borderline significance at 24 h (F (2,48) = 2.96, p = 0.056, η 2 = 0.052), significant at 48 h (F (2,48) = 3.54, p = 0.032, η 2 = 0.062), and borderline significance at 72 h (F (2,48) = 2.74, p = 0.069, η 2 = 0.048).

Post-hoc comparisons showed that MCL1 scored the lowest, which was significantly lower than that in MCL2 and MCL3 (p’s < 0.001) and there was no significant difference between MCL2 and MCL3, although it approached significance (p = 0.056, Holm corrected) (Fig. 2 d).

However, when adjusted for ABSI, FIB-4’s effect size decreased and became borderline significant (OR = 1.455, p = 0.056), indicating that its predictive role is secondary to burn severity.

The slight bilateral increase of FD in FS M1 only approached significance ( FaReMuS Treatment F(1,17) = 4.201, p = 0.056, Table 2 ).

Elk’s F IS was significantly lower than VA (Kruskal–Wallis, p = 5.535e-05) but the post-hoc Dunn’s test was only nearly significant (p = 0.056; Fig. 2 b).

The repeated measures analysis for the effect of predictability showed a trend-level main effect of predictability, F (1,31) = 3.96, p = 0.056, ω 2 = 0.013, which indicated attenuation of N1 amplitude for tones in the high predictability condition.

Sleep duration did not significantly correlate with complications ( p = 0.375; RR = 1.051), and those reporting satisfactory health status approached significance ( p = 0.056; RR = 1.149).

A higher BMI showed a trend towards a subsequent MS diagnosis following ON (OR 1.1074, 95% CI [0.998, 1.115], p = 0.056), (Fig. 2 , Supplementary Tables 1 , 2 ).

The post-hoc pairwise comparisons showed that the global efficiency of the PN + , CN- and CN + conditions are significantly higher than the baseline (all post-hoc p s < 0.016), while the difference between the PN- and the baseline is marginally significant ( post-hoc p < 0.056).

BDNF protein levels showed a trend towards upregulation ( P = 0.056), while expression levels for Bdnf were significantly downregulated in the cortex of LRRK2 KO mice (Fig. 7 A 1 and B 2 ).

The difference in ownership ratings was not significant when comparing Reference to Adult-like avatar (p = 0.209) and showed a trend for being greater for the Reference compared to the Child-like avatar (p = 0.056).

Indeed, when compared across the experimental phases, cerebellar cTDCS significantly impaired motor adaptation of the proximal upper-limb compared to M1 stimulation, with a near-significant impairment compared to sham ( p = 0.056).

There was a marginally significant interaction between the prognostic impact of a decrease in eGFR and the choice of diagnostic imaging modality (interaction-p = 0.056).

When pooling both training groups (dual-task and single-task training group) we found an almost significant correlation ( r (32) = 0.331, p = 0.056) controlling for age and sex.