Barely Significant

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a clear trendP = 0.051.0× alphagold
Notably, significant upregulation of the keratinocyte terminal differentiation marker filaggrin (FLG; + 308%; P < 0.001) and a clear trend towards an increase (+ 132%; P = 0.05) in transcript levels of the epidermal differentiation complex protein loricrin (LOR) was observed in skin from SGC707-treated mice (Fig. 4 C).
highly significantp < 0.051.0× alphaqualifiedgold
This equates to an odds ratio of 1.2 – 1.4; in other words, the odds of participation is 1.2–1.4 times higher given a 1-unit increase ‘intrinsic (pro-nature) motivation.’ Native Hawaiian ethnicity was also highly significant and positive in two of the models ( β = 1.6 ± 0.6, p < 0.05 at 0.25% payment threshold and β = 2.0 ± 0.7, p < 0.01 at 0.5% threshold), equating to an odds ratio of 5.0 and 7.4, respectively.
nominally significantp<0.051.0× alphagold
Pooled analysis Metabolites with nominally significant differences (p<0.05) and trends (0.05<p<0.10) between screening and Year 3 within the FP and AP groups Metabolites that were nominally different are reported in Table 2 with circulating concentrations reported in Table S1.