Excerpts

The effect of Rab27a on prognosis was only marginally significant in WHO Grade II gliomas in CGGA ( Figure 2A ) but was significant for the WHO Grade II gliomas in the Rembrandt cohort ( Figure 2D ).

At the level of species within orders, however, we found a negative relationship that reached borderline significance: species from smaller orders tended to have a higher mean research effort than species from larger orders (Spearman rho between the number of species per order and the average number of publications per species within each order = −0.354, p = 0.055, Figure 2b ).

Nevertheless, future studies should be conducted to determine whether a significant trend might emerge using longer delays (and perhaps a fully within-subjects design).

Then, we assessed liver cell apoptosis and found an extremely significant increase in TUNEL positive cells in BPA-treated rats at 15 and 21 weeks, which accompanied by a modest increased level of serum ALT observed at 21 weeks.

P-values <0.01 were considered as statistically highly significant (indicated by double symbols: *, # or Δ).

In all the eight health domains (mobility, self-care, pain and discomfort, cognition, interpersonal relationships, vision, sleep and energy, and affect), the prevalence rates followed a positive trend.

We do indeed observe a correlation between mitochondrial synonymous diversity and allozyme diversity both across the whole dataset and within each group of organisms ( Table 1 , figure 1 ), with many of the correlations being significant or nearly significant.

PLPtg/PD-1-/- double mutants, compared to PLPtg mice, showed a clear trend of increased vacuole numbers (13.3±7.9 versus 7.95±3.6), while wt and PD-1-/- mice never displayed any vacuoles (data not shown).

PLPtg BMCs transplanted with PD-1-/- bone marrow showed a highly significant increase of axonal damage ( Figure 2F, G, H ).

In the irradiated PLPtg mice statistical significance was reached, while the PLPtg/RAG-1-/- mice showed a trend into the same direction but did not reach the level of significance (p = 0.06).

In the Caucasian cohort, SNPs located close to or within the CFTR gene were highly significant in this GWAS analysis.

In white light, two QTL were significant, with a major-effect QTL detected on the top of chromosome 5 ( Figure 5C ), while in far-red light, a single marginally significant QTL was detected on the bottom of chromosome 4 ( Figure 5D ).

This difference was significant in P1, P2 and P3, and marginally significant in P5 (two-tailed t-test).

p value of less than 0.05 and 0.01 was considered significant and highly significant respectively.

The near-significant correlation between increases in roe deer density and incidence of TBE in the alpine provinces of north-eastern Italy partially supports our hypothesis that large vertebrate hosts could play a crucial role in TBE upsurge.

As previously reported [1] , there was a highly statistically significant correlation with the TGF-β codon 10 CC genotype, and a moderately significant association with meconium ileus status.

The detailed analysis showed a clear trend towards decreased number of TLR4 positive insulin producing cells in diabetic mice that coincided with a statistically 3-fold increase of TLR4 positive macrophages locally in the islets.

A p-value <0.05 is described as significant and a p-value <0.01 as highly significant.

When we compared our results obtained by the quantification of the CD31- immunoreactive endothelial area with micro vessel density or Chalkley counting in 120 spot areas we found a strong and highly significant correlation in both cases ( Fig. 2A,B ).

found a similar correspondence (Spearman's rank correlation: r = 0.501, n = 45, p<0.001), and used this highly significant correlation to justify mixing the two datasets.

5A,B ) with very few in non-CM cases ( Table 1 ), the difference being highly significant.

When samples were grouped into northeast Asians and southeast Asians (excluding Koreans), a highly significant difference was found between the two groups with all markers.

One potential explanation for the larger observed BP reduction in the intervention group is that CAHE led to an improved adherence to lifestyle recommendations, which is also supported by a positive trend of small improvements on BMI and sodium reduction in the intervention group.

found significant gray matter reductions in the frontal and temporal brain regions in psychopaths compared with controls, especially a highly significant volume loss in the right superior temporal gyrus [42] .

This question is both scientifically and practically significant because it not only depicts the logic behind the network architecture, but also helps us uncover the potential control points of signaling networks for drug design.