Excerpts

Although we did not observe a significant difference in DCA levels, there was an increasing trend, which might cause more damage to the liver and promote ICP development.

2a ) showed that the single-cell protein identification number showed an increasing trend with the increase of the enzyme/protein ratio.

We observed a decreasing trend in CDCA levels in the small intestine of B. fragilis -colonized mice, which might further contribute to the reduced intestinal FXR signaling.

We performed separate principal coordinates analysis (PCoA) based on Bray-Curtis dissimilarity and the Permutational multivariate analysis of variance (PERMANOVA) analysis, which revealed highly significant differences in both virulent ( R 2 = 0.42) and temperate ( R 2 = 0.63) phage communities between the gibbon family groups (Fig. 3a ).

After the sacrifice, we also observed a positive trend in the spleen weight in CCl4-treated animals, compared to control mice, immediately after CCl4 treatment cessation, at week 14, but they did not reach statistical significance (Supplementary Fig. 3B ).

Except for foothills, the indices of human activity show a decreasing trend from the Early Modern (460 yr cal BP; 1490 CE); probably related to progressive agricultural abandonment of mountain environments 59 leading to a gradual return of forest cover 17 , 60 , which may also have been favored by climate change 61 .

Additionally, the pump fluence dependence of propagation efficiency for a coupling angle of 0° displays an increasing trend from 20.88% to 39.00% as the pump fluence increases (Supplementary Fig.

Likewise, the A3’SS and A5’SS events exhibit a slight trend towards inclusion, consistent with the high frequency of RIs (Fig. 3B ).

No statistical difference in the (N/C) poly A + fluorescent intensity ratio was identified between THOC6 affected and unaffected control hNPCs, while a highly significant increase in the N/C poly A + signal intensity ratio was measured in THOC6 +/+ hNPCs treated with WGA attributed to high accumulation of poly A + RNA in the nucleus (Fig.

As age increases, we observed a decreasing trend in the levels of circulating progesterone steroids sulfate metabolites in both men and women.

In contrast, a positive trend of abundance with marine heatwaves for trophic groups with a STI below the threshold could indicate a transient stage where warm-water species have not yet established, and native species with low STI values are resisting intensifying marine heatwaves.

Most intermediates showed a trend of decreasing toxicity, although a small percentage remained toxic.

We note that the correlation is highly significant but quantitatively moderate.

There are few OS events in either arm, but a positive trend towards improved OS is seen with pertuzumab compared with placebo.

Although those members show a strengthening of variability during the SSP370 scenarios, barely significant at 0.05 confidence level (Fig. 1d and Supplementary Fig. 13b ), the amplitude of strengthening is much smaller (4.1% relative to observation).

These differences were highly significant, encompassing the entire Mr ROI (Fig. 7c ).

However, we noted that increased level of SCNN1B expression was associated with numerically lower and nominally significant risk for hyperkalaemia in UK Biobank consistent with the lowering effect of upregulated ENaCs on circulating levels of potassium (Fig. 2H and Supplementary Data 5 ).

As an overall trend, mutant alleles accumulated progressively in the Maternal-F lineage until virtually no WT alleles remained, while in Paternal-F lineage, even at the endpoint of adulthood, approximately 60% of WT alleles persisted, in line with our single time point experiments (Fig. 4a, d , Supplementary Fig.

As expected, there was a larger number of trials (8/75) that had an insignificant (7/75) or marginally significant (1/75, whether it is significant depends on not correcting for multiple tests) sex comparison relegated to the supplementary information; hence, Trialtrove curators missed the sex comparisons in those 8/75 publications.

Statistically significant main effects were subject to Tukey’s highly significant difference (HSD) multiple comparison procedures to assess differences between factor levels.

Electronic and coordination structure analysis The oxygen vacancy concentration in Ru/TiO 2 , Ru/Ti 4 O 7 , and Ru/TiO shows an increasing trend due to the different stoichiometric ratios of Ti and O (Fig. 3a ).

Since the O w ions are adsorbed on Ca ions, the O w -H ab bonds exhibit an increasing trend that is similar to the Ca-O w bonds.

Specific expression of unc-23 cDNA in epithelia, or the epithelial-expression of mouse BAG2, but not unc-23 expression in CEPsh glia or muscle, results in highly significant rescue of the CEPsh glia defects in unc-23 mutants (Fig. 4e ).

Most recorded locations showed a trend for a stronger single-pulse EP compared to steady-state EP, in contrast to the prediction of the superposition hypothesis.

Although the oePCs showed a decreasing trend in DI values, they remained significantly higher than those of the cPCs, suggesting that oePCs were capable of maintaining their ability to differentially encode investigatory intentions across multiple days.