Barely Significant

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highly significantqualifiedgold
Abstract Focusing on the literature progress since 2002, the present review explores the highly significant role that multicomponent reactions (MCRs) have played as a very important tool for expedite synthesis of a vast number of organic molecules, but also, highlights the fact that many of such molecules are biologically active or at least have been submitted to any biological screen.
Although the simulations presented here were unable to reach equilibrium owing to the relatively high computational cost, it was possible to trace a clear trend that is compatible with the experimental findings and, in particular, I have found the following: (i) starting from a completely neutral system, only a limited proton migration from the acetic acid toward the triethylamine is seen and the formation of the triethylammonium acetate ionic liquid occur