Barely Significant

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highly significantqualifiedgold
Even if the association between VES and increased mortality is well known, a recent study demonstrated highly significant mortality rates also associated with clustered ventricular arrhythmia, starting from 2 episodes within three months in patients with implantable cardioverter defibrillators (ICDs), and increasing proportionally with the number of arrhythmic episodes [ 4 ].
Neither access type nor closure device was significantly associated with major vascular complications; treatment with IVL remained associated with a lower, though borderline non-significant, risk of complications ( Table A1 ).
In the same region, a similar observational study conducted approximately in the same era concluded that after a follow-up of 4 years, CTO recanalization not only significantly improved quality of life, in terms of physical activity limitation, frequency of angina and greater treatment satisfaction, but also showed a trend towards better cardiac survival and significant lower risk of MACE compared to that seen in patients with failed procedures [ 38 ].