Excerpts

We also see a positive trend in 2022.

In a highly significant model (R2 adjusted 0.796, p : 0.0001), progressive patients, both PP at diagnosis and progressive over time (SP and PP) with a higher EDSS at baseline, were at higher risk of accumulating disability over time ( Supplementary Materials Table S4 ).

Patients exposed to DMT at any time and/or with DMT at T1 showed a trend of lower disability, and EDSS was statistically lower in patients with DMT at T1 ( p : 0.049).

On the other hand, two prospective cohort studies merely found a nonsignificant trend toward greater cognitive decline among HI participants over an observation time from 2 to 5 years [ 32 , 45 ].

An elevated trend based on the snoring frequency in the prevalence of metabolic disorders among residents from southeast China was also noted.

In rural Korean communities, an increasing trend of ORs for the MetS of different snorers was reported (OR = 1.42 for rare snoring; 1.79 for occasional snoring; 2.03 for habitual snoring) [ 16 ].

Multivariable analysis confirms a significant trend over time in the use of decurarization, when controlling for other variables, with odds ratio for pharmacological decurarization increasing by 24% (14–34%) in 2017, 47% (36–59%) in 2018, and 59% (47–72%) in 2019, as compared with 2016 ( p < 0.001).

aeruginosa to imipenem was lower than that reported by CHINET [ 21 ] and showed a trend of decreasing first and then increasing, which was consistent with a previous report [ 22 ].

Other authors found highly significant correlations for the thigh after self-help treatment with a vibration device [ 37 , 38 ].

Since its inception over 50 years ago, trabeculectomy has been the most common glaucoma surgery performed globally [ 3 ], although studies from the United States have demonstrated a decreasing trend in trabeculectomy cases in favor of newer surgical techniques such as minimally invasive or less invasive glaucoma surgical devices [ 4 ].

In the final model, each joinpoint indicated a significant trend change, and the APC was obtained in each of the segments delimited by the joinpoints, using the weighted least squares technique.

Pooling data on ED visits using the random effect model showed a trend towards lower odds of ED visits in the electrical arm; however, this effect did not reach the level of statistical significance for the differences across the two groups (OR 0.50, 95% CI 0.14 to 1.74; n = 621; I 2 = 57%) ( Figure 4 ).

Indeed, unlike Fried, we found almost significant relationships between the number of symptoms probed by a questionnaire and the mean overlap, suggesting that questionnaire length is involved in determining overlap [ 23 ].

Probiotic supplementation resulted in a decreasing trend for the facial sebum excretion rate and increased TEWL overall.

In addition, p -values were considered significant if they were less than 0.05 and are reported as approaching significance if between 0.05 and 0.2.

Although a numerical trend was observed, no statistically significant differences were observed in the 6MWT, NT-proBNP, or the total number of PH-specific drugs.

Although relatively rare, the incidence of combined SCLC has shown an increasing trend.

Conversely, an increasing trend, was observed in another 9 regions.

There was a decreasing trend observed in 12 of 21 regions.

This research has practical significance in the context of an increasing trend to replace surgery with non-surgical therapies.

Along with the insignificant but positive association between DHEA-S and susceptibility (OR = 0.94, 95% CI: 0.67–1.31, p = 0.703), the results showed a possible trend between DHEA-S and COVID-19; DHEA-S had an increased OR and significance level for the three COVID-19 phenotypes (susceptibility, hospitalization, and very severe respiratory syndrome).

However, for the larger particle sizes, no significant difference was apparent in comparison to the surgical mask.

On the other hand, there was increased risk of adverse outcomes in the immediate postoperative period, such as dialysis and stroke (marginally significant) in post-heart-transplant patients who received pacemakers.

This has been confirmed by further research, where an increasing trend in the delta band power was observed from PD-CogN to PD-MCI and to PDD [ 39 ].

PD patients, compared to HC, showed significantly lower concentrations of NAA in the motor cortex, while the Cho levels showed a decreasing trend.