“an elevated trend”

In addition, we found evidence of high GNA12 expression in multiple sets of colorectal RNA-seq data ( GSE107593 : P = 7.48 × 10 −9 , LogFC = 0.42; GSE117993 : P = 6.76 × 10 −7 , LogFC = 0.27; GSE166925 : P = 1.09 × 10 −3 , LogFC = 0.52) and suggested an elevated trend in myeloid cells ( GSE162335 : P = 3.71 × 10 −13 , LogFC = 0.42).

Further subgroup analyses disclosed that in PASI75 responders, miR‐146a expression also showed an elevated trend throughout these four time points ( p < 0.001) (Figure 3B ); while in non‐PASI75 responders, the increasing trend of miR‐146a expression was not significant throughout these four time points ( p = 0.124) (Figure 3C ).

Results Meta-analyses revealed an elevated trend in SERPINE1 expression levels in TCGA [standard mean difference (SMD) =0.95; 95% confidence interval (CI), 0.53–1.36; P<0.001].

Further analysis showed that expression of MerTK in both CD56 dim and CD56 bright NK cells had an elevated trend in SLEs when compared with HCs (CD56 dim : 209.8 (90.9–557.3, p<0.001 vs 70.4 (47.5–156.3); CD56 bright : 419.3 (143.4–5905, p=0.040 vs 198.3 (108.0–607.1)) ( figure 1E ).

edulis showed an elevated trend under warming ( p = 0.001 for temperature effects) but did not under OA ( p = 0.30) (Figure 5a ; Table 2 ).

Conversely, male offspring from RUPP dams exhibited an elevated trend of circulatory glucagon ( p = 0.003).

The results showed that the expression of c-kit mRNA and SCF mRNA in the tail-hanging group was significantly lower compared with that in the control group ( P < 0.0001; P < 0.001), and the expression of c-kit mRNA and SCF mRNA in the tail-hanging group presented a trend of elevation with significant difference ( P < 0.01), and that in the tail-hanging group the expression of SCF mRNA in the probiotics The expression of SCF mRNA in the tail-hanging group showed an elevated trend with significant difference ( P < 0.01), The expression of c-kit mRNA in the probiotic tail-hanging group showed an elevated trend, but there was no significant difference ( P > 0.05; Figure 2 ).

The expression of CD34 mRNA in caput epididymis tissues of yaks compared to corpus and cauda showed an elevated trend ( p < 0.01).

The ratio of β 2 -MG/MA presented an elevated trend in both the euhydrated group (Z = −2.23, p = 0.026) and the dehydrated group (Z = −2.72, p = 0.007), while the prevalence of elevated ratios of β 2 -MG/MA in the euhydrated group were higher than that in the dehydrated group, though this may have been due to chance ( Table 3 ). 4.

Lymphocyte subset monitoring showed an increasing trend in CD8+ T and B cells after CIK cell therapy ( P > 0.05) and an elevated trend in NK cells after NK cell therapy ( P > 0.05).

Notably, Pg application did not significantly increase the proportions of B/plasma cells or macrophages ( p > 0.05), and neutrophils showed an elevated trend with no statistical significance ( p > 0.05) ( Figure 5 D).

While PC3 showed an elevated trend in ASD-only (Cohen’s d = 0.195) ( Figure 12c ), it remained non-significant (p > 0.05).

With ascending quartiles of TIR, downtrends were observed in the prevalence rate of diabetic retinopathy, ACR, HbA1C(%), SD, MODD, MAGE, MBG, ADDR, M value, and CV of type 2 diabetes patients(P < 0.05); on the contrary, Male proportion and UREA value showed an elevated trend (P < 0.05).

Compared to those in the CON group, lactating cows in the trial groups showed an elevated trend in all the indicators except for non-fat milk solids and ash, although treatment, linear, and quadratic differences were not observed ( p > 0.05). 3.3.

Interestingly, butyrylcarnitine (C4) showed an elevated trend in the GR group after probiotic supplementation ( P < 0.05 by the Wilcoxon signed-rank test; Supplementary Fig. 7 and Supplementary Table 8 ), which is consistent with our early report that butyrylcarnitine (C4) was increased in older women supplemented with L. reuteri ATCC PTA 6475 compared to placebo 16 .

Adenine intake activated the oxidative stress Compared with the NC group, MDA level of kidney tissues in the NML group showed an elevated trend ( P > 0.05), while in the NMM and NMH groups was considerably higher ( P < 0.05; P < 0.05) ( Fig. 3 F).

Figure 1 B,C shows that the cooking loss and centrifugal loss had the same tendency as the thawing loss, and all the three indexes showed an elevated trend with increasing number of F-T cycles ( p < 0.05).

HD group showed an elevated trend p = 0.0706.

No significant difference in serum FGF-21 levels was observed between CHD patients with hypertension (462.2 ng/l, [59.1–2614.9], n = 97) and CHD patients without hypertension (428.2 ng/l, [77.8–1069.2] n = 38), despite an elevated trend in these CHD patients with hypertension (P = 0.0718, Figure 1C ).

Similarly, the patients with PH‐HFrEF with increased PAWP also showed an elevated trend of E/e′ (increased PAWP vs. decreased PAWP: 17.8 ± 5.9 vs. 13.9 ± 3.8, P = 0.08).

However, phosphorylated ERK (Thr980) levels showed an elevated trend in the CYP substrate + CYP inducer group compared to the NON-CYP + CYP substrate group ( p = 0.08).

Serum NGAL levels showed an elevated trend in subjects with overweight/obesity ( P = 0.085, presented in Additional files 1 , 2 ).

The expression levels of Sphingosine-1-Phosphate Lyase 1 ( SGPL1 ) and Phospholipid Phosphatase 3 ( PLPP3 ) showed a significantly higher ( P = .006) and an elevated trend ( P = .09), respectively, in the corpus callosum of patients with schizophrenia compared with controls ( figure 2B ).

The reduced 30-min insulin response resulted an elevated trend for plasma glucose levels at 60 min (dominant P = 0.09, adjusted for age, sex, and percent body fat; Fig. 1 C ).

However, earlier analysis of the chow-fed animals found that CRHR2 exhibited an elevated trend when the same data was normalized by GAPDH ( t [ 5 ] = 2.008; p = 0.09).