Excerpts

Mixed-model crossover analysis confirmed a highly significant treatment effect on both N35–P50 and P50–N95 amplitudes with no evidence of carryover.

Our hypothesis is that respiratory function and muscle strength may be significant predictors of mortality.

Although not reaching statistical significance, there was a favorable trend toward slowed global VF MD progression after supplementation began, suggesting a possible neuroprotective effect.

Our analysis confirms high flap survival rates, even in emergency scenarios, and demonstrates a clear trend toward improved outcomes over time—likely attributable to greater surgical experience, technical refinements, and more accurate preoperative planning.

The headache burden among pediatric and adolescent patients is also significant and shows an increasing trend [ 14 , 15 , 16 ].

Conclusions: In advanced ampullary adenocarcinoma, despite higher toxicity, frontline FOLFIRINOX showed a trend toward an OS benefit in the intestinal subtype while providing a similar outcome in the pancreaticobiliary subtype.

In summary, the completeness of follow-up was significantly associated with the PAD stage and showed a trend with age.

As shown in Figure 5 , there is a clear trend of increasing severity of diastolic dysfunction (Grades II and III) with greater CAD burden, particularly in patients with two- and multivessel disease.

We consider this finding an improvement upon the AUROC presented in our first report [ 2 ], where we demonstrated a trend toward significance but did not meet the threshold for statistical significance ( p = 0.057) and had broad 95% confidence intervals (0.571 to 1.009) in the logistic regression.

0.069, p = 0.063, Figure 2 a); however, a decreasing trend was observed ( Figure 2 a).

A recent meta-analysis also showed a trend toward lower rates of reconstructive failure, seroma, hematoma, flap ischemia/necrosis, and late rippling with ADM-based pre-pectoral reconstruction, though differences were not statistically significant [ 14 ].

While EPR showed a trend toward higher satisfaction and fewer reinterventions, the increased complication rate highlights the importance of careful patient selection and counseling about potential risks.

This represents a remarkable improvement over the best conventional score, the pre-endoscopic Rockall, and the difference in performance was highly significant. The ability of the ML model to attain high sensitivity and specificity simultaneously is particularly valuable in the emergency setting—it enables identification of high-risk patients without over-triaging those at low risk.

Discussion A decreasing trend in the number of patients with epistaxis was observed over 4 years, where slightly over 400 patients were received in 2015 and around 300 in 2018.

Although there was no statistically significant difference in BMI, only the old female group showed a trend toward lower calf circumference (CC: −0.29) in the LSS group.

The emergency room reduction for HIE products across all insurance payer types was not significantly significant.

In our study, the EI reached statistical significance on univariate analysis and remained borderline significant in multivariate modeling, suggesting that lesion geometry may influence heat distribution and ablation completeness.

[ 47 ] reported a marginally significant benefit of add-on Citalopram specific to negative symptoms.

Interestingly, sport type was not significantly associated with MSD prevalence in the current sample, though participation in team sports approached significance.

Age, on the other hand, showed a clear trend toward a negative association with cognitive outcomes.

However, there was a clear trend of better pregnancy outcomes in the group with GnRH antagonist administration from day 1 of IVF stimulation.

A significant trend in the reduction of mechanical versus biological prosthesis implantation was observed during the study period (2000–2021).

There was a borderline significant trend towards a higher proportion of patients receiving oral corticosteroid therapy in the COVID-19 group compared to the negative group—35 vs. 30 patients (χ 2 = 3.2, p = 0.051).

Firstly, the correlation between WPI and HADS was weak, with a tendency toward statistical significance.

However, the occurrence of new strokes exclusively in the MMD subgroup suggests a possible trend toward more aggressive disease in idiopathic cases, although statistical confirmation was limited by the small sample size.