Excerpts

In summary, the completeness of follow-up was significantly associated with the PAD stage and showed a trend with age.

As shown in Figure 5 , there is a clear trend of increasing severity of diastolic dysfunction (Grades II and III) with greater CAD burden, particularly in patients with two- and multivessel disease.

A recent meta-analysis also showed a trend toward lower rates of reconstructive failure, seroma, hematoma, flap ischemia/necrosis, and late rippling with ADM-based pre-pectoral reconstruction, though differences were not statistically significant [ 14 ].

This represents a remarkable improvement over the best conventional score, the pre-endoscopic Rockall, and the difference in performance was highly significant. The ability of the ML model to attain high sensitivity and specificity simultaneously is particularly valuable in the emergency setting—it enables identification of high-risk patients without over-triaging those at low risk.

Although there was no statistically significant difference in BMI, only the old female group showed a trend toward lower calf circumference (CC: −0.29) in the LSS group.

The emergency room reduction for HIE products across all insurance payer types was not significantly significant.

In our study, the EI reached statistical significance on univariate analysis and remained borderline significant in multivariate modeling, suggesting that lesion geometry may influence heat distribution and ablation completeness.

[ 47 ] reported a marginally significant benefit of add-on Citalopram specific to negative symptoms.

Interestingly, sport type was not significantly associated with MSD prevalence in the current sample, though participation in team sports approached significance.

Age, on the other hand, showed a clear trend toward a negative association with cognitive outcomes.

There was a borderline significant trend towards a higher proportion of patients receiving oral corticosteroid therapy in the COVID-19 group compared to the negative group—35 vs. 30 patients (χ 2 = 3.2, p = 0.051).

However, the occurrence of new strokes exclusively in the MMD subgroup suggests a possible trend toward more aggressive disease in idiopathic cases, although statistical confirmation was limited by the small sample size.

Studies suggested that neurocardiac pathophysiological pathways may be significant in understanding neuropsychiatric symptoms in athletes with heart disease.

In head and neck cancer, patients with non-cardiac irAEs in our study showed a clear trend toward improved OS and PFS, although statistical significance was not reached.

Additionally, a pivotal RCT that compared 0.05% CHG with TAS breast pocket irrigation for PMBR with TEs showed no significant difference in SSIs, though TAS approached significance for lower rates of infectious complications [ 16 ].

The PSSI subscale “critical–negativistic NT” ( β = −0.327, p = 0.016) significantly impacted HAMD-21 change scores, while the influence of the “reserved–schizoid SZ” subscales ( β = 0.256, p = 0.058) was only marginally significant.

MTR maps have a very flat, even contrast; their value as a biomarker comes from the fact that relatively small changes are usually highly significant compared to the uniform background.

Among these, LAScd ( p = 0.019) and SBP ( p = 0.083) remained significant or near-significant after correction, confirming limited overfitting and good internal consistency of the final model ( Supplementary Materials Table S1 ).

Reflecting this dynamic, the OSDI in our study showed a more pronounced postoperative improvement compared to the DEQ-5, which reached only borderline significance.

In terms of visual outcomes, BCVA did not change after one or two injections, but showed a trend toward decline after the third injection.

It was also linked to greater “ motor delay ” (r = −0.207, p = 0.016), and there was a clear trend toward more severe “ cognitive delays ” (data upon request).

While sex- and age-related differences were modest, associations with DAL severity were highly significant ( Supplementary Table S1 ).

In the Henderson model, ΔHCO 3 is strongly positive and ΔPCO 2 strongly negative—both highly significant—consistent with the Henderson–Hasselbalch framework.

All of these correlations were highly significant, with a p -value of <0.001. 4.

Significance was defined as a p -value of less than 0.05, highly significant as a value of less than 0.01, and the highest significance as a value equal to or less than 0.001.