Excerpts

The polymorphisms rs1052133 and rs207454 show a trend toward significance in the OS analysis when the patients were ER+ ( p = 0.077 and p = 0.053, respectively) ( Figure 2A,B ).

Tumor mRNA level of PDGFRB was significantly associated with serum PDGF-BB (R = 0.395, p = 0.009) and marginal significance with serum PDGF-AA ( p = 0.077; Figure S1D,H ). 2.4.

Hsa-miR-3605-3p showed a trend towards a 2.10 ± 0.48-fold increase in superior ROs compared to inferior ROs ( p = 0.077).

SFC+ mice also showed a trend towards a lower expression of Npy in the DR ( Figure 5 d, T(16) = 1.636; p = 0.077).

The association of carnosine-propanol with heart failure was nearly significant in the unadjusted model ( p = 0.077), but gained in statistical significance after adjustment ( Table 6 : regression coefficient = 0.803; p = 0041).

Another review of 65 patients, of which 17 patients were treated with cetuximab-including regimens, showed a trend for improved response (OR = 5.05, p = 0.077) when compared to those who received taxane-based regimens alone [ 52 ].

The interaction term between electrical stimulation and hypoglycemia nonetheless showed a trend towards significance (t = −1.7898, p = 0.0776), implying a potential interaction effect between the two predictors.

Although the spectra for the first derivative are mostly overlapping, nearly significant changes in the spectral intensities could be found between the benign and malignant prostate tissue at 1113, 1120, and 1994 nm ( p = 0.0776, p = 0.0667, and p = 0.0848, respectively; Figure 5 A–C).

The mRNA expression of XIST was almost significantly downregulated ( p = 0.078), and the transcript levels of the four tested X-linked genes were significantly increased in the 4-cell stage of embryos with YY1 knockdown compared with the control embryos ( Figure 5 D).

Median OS reached borderline significance (30 months for HER-2 score 0 vs. 16 months for HER-2 1+/2+/3+, p = 0.078).

Patients with MetS showed a trend toward a higher WBC count ( p = 0.078) in comparison to controls.

Metformin treatment also showed a strong trend towards enhanced posterior wall thickness compared to SD hearts ( p = 0.078).

Overall, the results showed that CD4 + T cells and CD8 + T cells had a statistically significant positive correlation (correlation coefficient r = 0.73, p <0.05) and a moderate positive correlation with a trend towards significance (correlation coefficient r = 0.49, p = 0.078) in PII-A and PII-C, respectively ( Figure 5 H).

In PreDM, ST shows a positive trend with BMI, approaching statistical significance ( p = 0.078).

PERMANOVA analysis revealed a borderline significant difference in centroids between groups ( p = 0.078), which was less apparent at the baseline ( p = 0.341).

The results of the correlation analysis between miR-542-3p and the genes under study indicate a slight trend towards a negative correlation between miR-542-3p and BMP7 in ectopic tissue (Rho = −0.358462, p = 0.078483) (see Figure 2 ).

A near-significant decrease was also found in the CUMS SUP group compared with the control SUP (−0.0780 ± 0.03, p = 0.0786).

An increase in both miR-375-3p and miR-382-5p was also seen in the Graves’-derived sEVs compared to the benign sEVs; however these increases only approached significance ( p = 0.0788 and p = 0.0683, respectively).

dUTPase-high HCC was also associated with high serum AFP values (≥100 ng/mL) with borderline significance ( p = 0.079, chi-square test).

CDCrel-1 immunoreactivity showed a trend toward a statistically significant decrease in the vesicular/cytosolic fraction after binge METH administration in the WT rats (−33%, p = 0.079, n = 5, multiple unpaired t -tests with Holm–Sidak correction for multiple comparisons) ( Figure 7 b).

Among short-chain fatty acids, hexanoic acid (C6) showed a trend toward higher levels in sarcopenic patients ( p = 0.079).

Although there were no differences in the ITT among groups ( Figure 2 A,B), the T + EEQ group showed a trend of improvement in glucose tolerance tests ( p = 0.079) ( Figure 2 C,D).

At the end of the study, both dietary treatments had reduced these biomarker levels; the control group showed statistically significant changes ( p = 0.007), and the RESMENA group showed a trend towards significance ( p = 0.079).

Additionally, a trend toward significance was noted for the negative correlation between IL-37 and IL-36Ra (R = −0.267, p = 0.0797).

PS128 administration significantly decreased the mRNA level of Nos2 ( Figure 3 C; p < 0.0001), and we further noticed a decreasing trend in the level of iNOS protein in the PS128 group compared with those in the Rot group ( Figure 3 G, p = 0.0797).