Excerpts

Surprisingly, compared to its corresponding media without WNT3A (BASAL), WNT3A-CM-RSPO1 significantly enhanced the expression of the CCND1 ( p = 0.0051) and c-MYC ( p = 0.0007) genes, while A+B only showed a positive trend compared to A ( p = 0.0689 and p = 0.1049, respectively) ( Figure 2 A).

For WT1_pre, relapsed patients showed a trend toward higher expression compared to non-relapsed patients (median 3.0 [IQR 3.0–39.5] vs. 2.0 [IQR 1.0–5.0], p = 0.069), although this did not reach statistical significance ( Figure 3 B). 2.6.

PT alone) and the combination of AgNPs plus PT induced a reduction in cell viability with borderline significance ( p = 0.069 vs.

When stratifying the plasma levels of immune-related hubs by previous treatments (topical, biologic, and other), a statistical trend was observed for IL-6 ( p = 0.069) ( Figure 6 E).

The group of CRF rats treated with rHuEPO, as compared to CRF rats without treatment, showed a trend ( p = 0.069) towards a reduction in mild tubulointerstitial lesions ( Table 3 and Figure 5 B3), but a significant increase in advanced lesions, namely in hyaline cylinders, calcification, necrosis and IFTA ( Table 3 and Figure 5 B6).

The mean of 5-hmC-positive cells/mm 2 for the epidermis and dermo-epidermal junction and the entire lesion differed significantly between DN and SSM ( p = 0.002 and p = 0.006, respectively) and showed a trend towards higher immunoreactivity in the dermal component ( p = 0.069).

Finally, in the group of participants with the GG genotype, we found a marginally significant increase in DBP at the pain threshold, b = 8.03, SE = 4.42, 95%CI [−0.64, 16.70], t = 1.82, p = 0.069, while the increase at pain tolerance was significant, b = 9.68, SE = 4.42, 95%CI [1.01, 18.35], t = 2.19, p = 0.029. 3.

Moreover, in the dominant model analysis, the frequency of rs1800693 TC + CC genotypes was also marginally significant between the severely and mildly ill patients (72.7% vs. 44.4%, p = 0.069) ( Table S2 ). 3.

Sham-irradiated male APP;E4F mice showed a trend towards fewer microhemorrhages than their non-traveled counterparts ( Figure 3 B, p = 0.0693).

In the recipient cohort, E-selectin (from 37 ± 19 to 34 ± 14 ng/mL; p -value = 0.0225) and PECAM-1 (from 79 ± 23 to 71 ± 15 ng/mL; p -value = 0.0016) decreased after transplantation while the reduction in vWF approached significance (from 181 ± 53 to 167 ± 57%; p -value = 0.0694).

Moreover, the 5G-exposed group of young adult rats also showed a trend toward decreasing ( p = 0.0696) PPAR α mRNA levels compared to those in the control group.

In mice given atorvastatin, gene expression of mitochondrial transcription factor ( Tfam ) was significantly reduced ( Figure 3 A), whereas the phosphorylated protein levels of serine/threonine kinase AMP-activated protein kinase (AMPK) showed a trend toward reduction ( p = 0.0696; Figure 3 B).

The higher amount of butyrate showed a trend for correlation with higher mtDNA ( p = 0.0698) ( Figure 7 h).

Gasdermin D revealed only a marginal trend to predict POD (OR 1.50 [0.97–2.32], p = 0.07), which faded when adjusted for covariates in models 2 and 3.

The same was true for hiPSC line CaSR, except for the fact that Perimeter only showed a trend towards statistical significance ( p = 0.07).

At the protein level, high NOVA2 expression showed a trend in association with the presence of lymph node metastases (chi-square 3.28; p = 0.07).

reported a marginal trend toward recovery ( p = 0.07), suggesting potential for future improvements.

Cin30 administration showed a trend toward reversing the Lac1-induced effect ( p = 0.07; Figure 5 B).

A marginal significance (0.05 ≤ p ≤ 0.07) is indicated by a symbol in parentheses. 5.

However, in MOLM-14 cells, shPSMD3 showed a trend for reduced NF-κB transcriptional activity, which was not further reduced by quizartinib therapy ( Figure 4 B; p = 0.07).

Stress Induced hyperthermia showed that Chd7 +/Whi mutants had a lesser response (+1.42 °C ± 0.13 versus +1.84 °C ± 0.16 in mutants and controls, respectively) although reaching marginal significance ( p = 0.07).

Notably, serum cholesterol levels showed a trend of decreasing in response to losartan ( p = 0.07) and mirabegron ( p = 0.08) compared to the DOXO-only group ( Table 2 ).

This trend was maintained albeit with borderline significance for aoSMCs (20% vs. 10%, p = 0.07, Fisher’s exact test) ( Figure 3 b).

While, generally speaking, there were no significant differences in the echocardiography parameters assessed ( Figure 3 A–I and Figure S7 ), there was a strong trend for LVPWd to be increased in Ang II ( p = 0.07 vs. saline) and high-dose Ang II + A331440 groups ( p = 0.06 vs. saline, Figure 3 C).

There were no significant differences in the subject characteristics (as outlined in Methods), though age was nearly significant ( p = 0.07).