Excerpts

The decrease in 95–100 kDa full-length species of ACE2 was also correlated significantly with GFAP (r = 0.31; p = 0.043), T-tau (r= 0.46; p = 0.002) and was close to achieving significance for NfL (r = 0.30; p = 0.051).

When analyzed independently of the control group, pooled samples from the two groups receiving malonate showed a trend of having higher succinate concentrations than those receiving RIC alone (repeated measures ANOVA, p = 0.051 for interaction), and significantly reduced levels of fumarate (repeated measures ANOVA, p = 0.014 for interaction and p < 0.001 for group allocation) and malate (repeated measures ANOVA, p = 0.019 for group allocation).

There was no change in RAD51 expression and a slight decrease in CHK1 in all BRCA1 clones, but only reaching marginal significance in BRCA1 exon-9.2 ( p = 0.051).

Compared to SSc-NCFS patients (0.47), SSc-CFS patients showed a trend of reduced expression of ND4 (0.34, p = 0.051) ( Figure 1 A).

TMEV-infected Mmp12 −/− mice showed transiently reduced astrogliosis in association with a strong trend ( p = 0.051) for a reduced density of activated/reactive microglia/macrophages compared with wild-type mice at 28 dpi.

Most importantly, a significant association of methylated PCDH8 level to tumor maximal diameter at diagnosis (R s = 0.35; p = 0.028) as well as borderline significance to tumor volume (R s = 0.32; p = 0.051) at diagnosis was identified ( Figure 3 A,B).

Women in PG had significantly higher triglycerides levels in the second trimester ( p < 0.05), while triglycerides concentrations in the third trimester were also higher in the PG but of borderline significance ( p = 0.051) ( Table 1 ).

However, after the inclusion of NT-proBNP (Model B), the association of GDF15 with all-cause mortality was attenuated, reaching borderline significance (HR 2.61; 95% CI: (0.99–6.87), p = 0.051), whereas NT-proBNP retained significance (HR 1.11; 95% CI: (1–1.22), p = 0.044) ( Table S2 ). 2.4.

In the comparison between the PE− and N− groups, our findings demonstrated a near-significant increase in ADMA levels in the PE− group ( p = 0.0512).

At P21, OA levels in the gastrocnemius and quadriceps showed no significant genotype differences under either normalization method ( Figure 3 A–D), although the gastrocnemius normalized to total protein approached significance ( p = 0.0515; Figure 3 B).

There was a trend towards significance for Gfra1 , with an increase in females ( Figure 1 , n = 6–8, p = 0.0517).

Paired comparison using the Wilcoxon signed-rank test (non-parametric) showed a strong trend toward higher CD34 expression in the subumbilical region, reaching the limit of statistical significance (U = 5.0, p = 0.0518).

In configuration 1 with a total of four wounds (n = 4) for each treatment arm that were performed across two pigs ( Figure 4 a), we found accelerated wound closure in the CLEC-treated group that was near significance ( p = 0.0518) based on repeated measures two-way ANOVA over time ( Figure 3 a).

In the Ac samples, the CD164+ subpopulation was significantly enlarged in the DDH-OA group, while in the pOA group, the CD10+ subpopulation was significantly enlarged and the GD2+ subpopulation was enlarged with marginal significance ( p = 0.0519).

Comparing EC IFs and ECs to all IFs, we found no significant differences either for IDPs ( Figure 4 , Supplementary Figure S2 ) or their partners ( Supplementary Figure S3 ), although the enrichment of the EC-carrying interfaces of IDPs in negative residues was nearly significant ( p = 0.0519).

Furthermore, in the univariate analysis, MAN1C1 high expression showed a trend association with better overall survival ( MAN1C1 high: 0.74; p = 0.052), as well as decreased disease-free survival, with a hazard ratio also of 0.74 ( p = 0.049).

Recruitment was higher in the MSt compared with both the HC and the NC (F (2,20) = 36.95, p < 0.0001), with marginally significant group x region interaction (F (2,20) = 3.43, p = 0.052; “group” refers to Control/ALAN groups, “region” refers to MSt/HC/NC).

Also, the number of events in the open arms was higher in the TMZ than in the MEL group ( p = 0.002, Figure 1 F), and it showed a trend toward a significant difference ( p = 0.052) compared with mice that received TMZ followed by MEL.

Testosterone levels were lower in male CRC patients (median 14.32) compared with healthy controls (median 17.69), with a trend toward significance ( p = 0.052; Mann–Whitney test).

A slight increase in plasma GFAP levels in ALS females compared to males almost reached statistical significance (179.43 (126.4–238) vs. 152.19 (110.4–231.9), p = 0.052).

ST32db showed a trend toward decreasing SREBP1 protein levels relative to the control group ( p = 0.052).

One study observed that the levels of serum IL-6 in patients with alcohol dependence did not significantly decrease although they showed a trend from baseline to 16-week follow-up ( p = 0.052) [ 70 ].

There was also a strong trend towards an increase in Young Adult Sleep Dis rats than Young Adult Normal Sleep rats ( p = 0.052).

For GR activity, the statistical analysis revealed a significant main effect for the group, which was almost significant (H = 5.655, p = 0.052).

In contrast, CD34 displayed higher sub-umbilical scores (median 3) compared with supraumbilical (median 2), with a strong trend toward significance ( p = 0.052) and a large effect size, suggesting increased microvascular density/activation in the sub-umbilical segment.