Barely Significant

Excerpts

8,476 sentences · 1 filter applied

Interestingly, eight JAZ subfamily genes ( PaJAZ1 , PaJAZ6 , PaJAZ7 , PaJAZ8 , PaJAZ9 , PaJAZ11 , PaJAZ12 , and PaJAZ14 ) all showed an increasing trend from the S1 to S2 stage (peaking at the S2 stage), followed by a decreasing tendency from the S2 to S4 stage, with relative expression levels reaching their lowest level, except for PaJAZ12 , which was equal to the S2 stage.
highly significantqualifiedgold
Summary In summary, our findings strongly indicate for the first time that the combination treatment with either PIK-75 or alpelisib with gefitinib is very effective against PIK3CA -mutated HER2-negative mGAC, a highly significant result given the paucity of targeted treatment options in HER2-negative mGAC.