Barely Significant

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Treatment with EGb 761 did not substantially reverse LPS-induced IκBα degradation, thereby failing to prevent phosphorylation and subsequent nuclear translocation of the NF-κBp65 subunit, although there was a slight trend towards reduced IκBα degradation, this effect did not reach statistical significance.
The nearly significant correlation between circulating intermediate monocyte frequencies and plasma IFABP levels in the relatively small number of macaques in our study validates the interrelation between gut barrier disruption and chronic innate immune activation during prolonged ART.