Excerpts

Total adipose tissue (TAT) showed a near-significant trend (OR = 1.01, 95% CI: 0.99-1.02, p = 0.080), indicating a potential but non-significant association ( Table 2 ).

However, the survival disadvantage associated with high NTRK1 was statistically significant in females (p=0.005) but only showed a trend in males (p=0.08), likely due to the smaller sample size of the male cohort.

However, the SCID subtype T-, B+, NK- was more frequently associated with disseminated disease (18.8%) than localized or regional disease (0.0%), showing a trend toward significance (p = 0.080) ( Table 3 ).

Although iNOS expression was marginally insignificant between Adv/GM-CSF treated and untreated tumors (p = 0.08).

One month after the third and fourth dose, the levels were 226 BAU/ml (IQR: 7.0; 294 BAU/ml) and 433 BAU/ml (IQR: 326; 798 BAU/ml) with the increase being borderline significant (193 BAU/ml, 95% CI: −22; 569 BAU/ml, p = 0.080).

IL-1α levels showed a statistical trend for association with low IP (p-value=0.08) ( Figure 3E ) and was significantly increased in infants with less abx (p-value < 0.01) ( Figure 3F ), more MOM feed (p-value <0.05) ( Figure 3G ), and later GA (p-value < 0.01) ( Figure 3H ).

The decreased ratio of ramified:hypertrophic microglia correlated with higher CII score [F(1,30)= 10.34; R 2 = 0.2564, p =0.0031] ( Figure 4J ) and the increased density of Gal3+ cells approached significant correlation with CII score [F(1,30)=3.263, R 2 = 0.09810, p =0.0809] but density of C1q+ cells did not correlate with cognitive impairment [F(1,30)= 0.1048, R 2 = 0.003482, p =0.7484] (data not shown).

Notably, Prdm1 mRNA showed a decreasing trend at 48 h (n.s., p = 0.081) and was significantly reduced at 72 h in Abcd1 -deficient CD4 + T cells compared with wild-type cells ( Figure 4B ).

Ofatumumab Among leukocyte populations, basophils showed a trend towards an increase (p = 0.081) with no other therapy-associated changes.

The model showed R2 = 0.37 (adjusted R2 = 0.21), with an overall trend toward significance [F(5,20) = 2.32; p = 0.081].

Although most diversity indices (Shannon, p =0.52; Simpson, p =0.4) showed no significant intergroup differences, the borderline significance of Richness ( p =0.081) and Chao1 ( p =0.081) indices suggested potential marginal differences in species richness between groups that did not reach conventional significance thresholds.

However, a marginally significant trend was observed regarding pathological grade ( P = 0.081).

Natalizumab-treated pwMS showed a near-significant reduction in CD4+ AIM+ cells at 5–6 months post-vaccination compared to the previous time point (p=.0826) but, following booster dose, the increased proportion of these cells was comparable to that seen following the initial vaccination (p=.0378) ( Figure 4D ).

Additionally, the SI was significantly elevated in CD8 + T-cells at T3, while a trend toward significance was observed in CD4 + T-cells (p = 0.083) ( Figures 5C, D ). 3.6.

Plaque carbamylation showed a borderline significant correlation with serum urea levels (r=0.45, p=0.083), whereas no correlation was observed with cardiovascular risk factors, including smoking.

On the other side, we did not find any main genotype effect in Arg1 haploinsufficiency except for an increasing trend in apoptosis ( p = 0.083, Figure 2K ).

A higher ratio of intratumoral to peritumoral CD3 + T cells showed a trend towards a positive impact on DFS (p=0.084), while an increased ratio of CD8 + T cells was associated with significantly better clinical outcome (p=0.014) ( Figures 7D, E ).

The score of the CTGF+ONA group was not altered compared to WT+ONA mice (p=0.993) but showed a mild trend towards a higher score in comparison to CTGF optic nerves (p=0.084; Figure 2B ).

When we included upper GI tract biopsies in our analyses, we still observed marked suppression of IL22 in antibiotic group with a trend towards significance (no Abx: median = 1.88, range = 0 - 898; Abx: median = 1.21, range = 0 - 85.8, p = 0.085).

RT+CpG+OX40 significantly increased the non-Treg CD4+:Treg ratio compared to treatment with RT alone and showed a trend (p=0.0851) toward an increased ratio when compared to PBS treated tumors.

Regarding GI surgery due to IBD, more patients with the GT genotype underwent surgical treatment compared to GG homozygotes ( Figure 2B ), although this difference was borderline significant before statistically correction ( p = 0.0851, p adj . = 0.2389, Table 3 ).

None of the genes were altered, although IL33 showed a trend toward increased expression (p=0.0857) ( Supplementary Figure 3 ), suggesting that co-culture is required for the EC effect on these genes to be evident.

The proportions of SM B cells and DN B cells were significantly higher, and the absolute count of naïve B cells showed a decreasing trend that approached statistical significance (33.01 [5.23–88.91] vs. 55.10 [25.93–94.92], P = 0.086; Table 2 ).

Similarly, a higher proportion of anti-Tg + PV subjects (n=14) contradict the DCH than anti-Tg - subjects (n=96) and all PV subjects (n=159) across all cutoffs (trending towards significance with Chi Square of p=0.086) ( Figure 4B ) .

There was also a positive trend for PFS, with an mPFS of 9.3 months (95%CI, 3.3–25.4) in the former group and 2.0 months (95%CI, 1.7–13.2) in the latter group ( Figure 5B ) ( p = 0.086).