Barely Significant
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“trend toward significance”

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trend toward significancep=0.0300.6× alpha
The lack of a significant association between malnutrition and sex (p=0.705) or animal contact (p=0.053) suggests that these factors may not directly influence nutritional outcomes in this cohort, although the trend toward significance for animal contact (48.3% exposure) and unprotected water sources (55.8%, p=0.030) points to environmental exposure that warrants further investigation in larger studies.
trend toward significancep = 0.051.0× alpha
Although the reduction at 6 weeks was not statistically significant ( p = 0.16), the decrease at 3 months showed a stronger trend toward significance with a 15.5% change in mean score ( t = −2.05, p = 0.05), with a low effect size (Cohen’s d = 0.3).
trend toward significancep ≈ 0.051.0× alpha
Age was significantly associated with hearing loss, which affected older individuals (85.55 ± 3.88 years) compared to those who retained it (83.94 ± 3.48 years) ( p = 0.002), and related to a higher frequency of physical activity among younger individuals (trend toward significance, p ≈ 0.05).
trend toward significancep -value < 0.051.0× alpha
GO terms that trend toward significance (i.e. nominal p -value < 0.05) similarly showed substantial discordance in direction of effect for some GO terms (Figure 2 E), where processes related to immune response, inflammation, blood brain barrier, extracellular matrix/membrane, and metabolism were increased in high stage disease but decreased in low stage disease.
trend toward significancep = 0.0511.0× alpha
Likewise, the association between knowledge level and belief in vaccine efficacy showed only a borderline trend toward significance (χ 2 = 12.53, p = 0.051), suggesting a possible but inconclusive relationship between stronger belief in vaccine efficacy and higher knowledge scores ( Table 10 ). 3.9.
trend toward significancep = 0.0521.0× alpha
Significant improvements in albumin (from 3.2 ± 0.5 to 3.5 ± 0.5 g/dL, p < 0.001), ALT (from 71.5 ± 60.5 to 25.5 ± 11.6 IU/L, p < 0.001), AST (from 92.6 ± 76.9 to 41.9 ± 18.3 IU/L, p < 0.001), total bilirubin (from 2.2 ± 1.2 to 1.8 ± 1.0 mg/dL, p = 0.015), INR (from 1.35 ± 0.3 to 1.25 ± 0.2, p = 0.02), and improvement in PT (from 14.5 ± 3.5 to 13.7 ± 1.9 s, trend toward significance, p = 0.052) were observed after successful DAA therapy.
trend toward significanceP = 0.05211.0× alpha
While somatic withdrawal did not reach significance in adolescent nicotine females compared to vehicle, they did trend toward significance (t(51) = 1.989, P = 0.0521), supporting previous work in mice that found increased withdrawal in adolescent female mice compared to adults [ 61 ].