Excerpts

Second, among participants with complete three-timepoint data at baseline, six months, and 12 months (n = 14), SF-BBS scores showed a positive trend over time.

Furthermore, individuals with AdipoR1 and AdipoR2 expression showed a trend toward decreased cancer-free survival [ 32 , 33 ].

In contrast, serum eNOS levels showed a decreasing trend with advancing stages of kidney disease.

Considering that the association between ISR and LS BMD gains was attenuated to marginal significance in the multivariate model, whether ISR serves as an independent predictor of treatment response remains unclear.

In the multivariate analysis adjusting for age, these associations were attenuated but remained marginally statistically significant.

By disease category, the mean number of errors per case showed an increasing trend in the order of MSK (six cases, one per case), CVA (three cases, two per case), and DUS (two cases, four per case).

Shoulder flexion active range of motion, a primary functional outcome, showed a positive trend in 6 of 10 patients, with an average gain of 12° (range: 3°-22°; e.g., patient 5: 118° to 140°, patient 10: 165° to 180°).

Hemodynamic monitoring showed a trend toward asymptomatic arterial hypotension; available documented blood pressure values remained within a similar low-normal range, including 106/66 mmHg on day three, without symptomatic hypotension or clinically significant hemodynamic instability.

52.6%; p = 0.051) showed a strong trend but did not reach statistical significance.

For instance, a single‐center study found only a nonsignificant trend toward higher readmission rates among obese PPCM patients, likely due to insufficient statistical power [ 11 , 16 ].

Although psychological well-being also demonstrated an increasing trend, this association did not reach statistical significance.

Interestingly, although psychological well-being showed a positive trend, the association did not reach statistical significance, indicating that emotional adaptation may be influenced by additional factors such as personality traits and social support.

Pulse rate remained largely unchanged with all three drugs, although azelnidipine demonstrated a numerical trend toward greater pulse-rate reduction.

A decreasing trend was observed in the frequency of exacerbations in both groups.

Cancer type was a highly significant correlate after adjustment for all other covariates.

Early-onset preeclampsia (≤34 weeks) showed higher odds (OR 1.53), which persisted after adjustment (AOR 1.71), suggesting a possible trend toward increased hemodynamic instability in severe disease; however, statistical significance was not achieved.

Multiple gestations showed a trend toward increased risk (AOR 4.34), though not statistically significant (p=0.058).

In this regard, the 2% GI side effects with imeglimin in this study, compared with the 20%-30% rate with standard metformin, are highly significant and a finding consistent with its distinct mechanism of action [ 6 , 20 ].

Although a positive trend was observed between RMS values of EMG and HGS, the association was not statistically significant; therefore, no definitive conclusion regarding the relationship between muscle electrical activity and grip strength can be drawn from the present data.

The greatest differences were observed between the supragingival and subgingival restorations, with all comparisons showing highly significant p-values.

Controlled-release oxycodone/naloxone resulted in slight pain relief that was almost statistically significant [ 21 ].

Moreover, a clear trend toward increasing scores was observed as lipid abnormalities became more pronounced, supporting an association between RBC/RDW, together with sex and BMI, and HDL-c and TAG alterations in ECR.

Paired t-tests demonstrated highly significant pain reduction at all follow-up points (Table 3 ).

Although cardiovascular parameters, such as blood pressure, showed an increasing trend, glycemic and lipid control remained stable, emphasizing the need for continued monitoring and management of cardiovascular health.

In multivariable analysis, only SJC remained independently associated with TTR ( P = 0.040), whereas ESR showed a nonsignificant trend toward association.