Excerpts

However, a slight trend can be observed, with patients receiving platinum/taxane-based treatments showing slightly lower recurrence rates compared to those treated with anthracycline-based regimens.

The positive rates of ER and PR in Taiwan were lower than those in the USA, but they exhibited an increasing trend with age.

Adherence to optimal laboratory-based triggers for transfusion (Hb values below 7 g/dL or below 8 g/dL in patients with prior history of Cardiopathy) was 31.5% along the years of the study, with a clear trend towards improvement reaching 69.2% in 2018 and without statistically significant differences among the groups ( p > 0.05).

Introduction Head and neck cancers (HNCs), an important clinical and epidemiological problem, show an increasing trend in both incidence and mortality.

Notably, in addition to the six focus cytokines that differed between the GEP classes (MCP-3/CCL7, PDGF-AB/BB, TNF-β, G-CSF, IL-13, and IL-3), two of the three cytokines that showed a trend for such difference (IL-4 and VEGF) also ended up in the same IPA networks ( Figures S2 and S5 ).

Finally, one study from China indicated that the tumor content of circulating cfDNA is related to the development of HBV-related HCC and presents an increasing trend during the 4-year period preceding clinical diagnosis of HCC, whereas it is correlated with tumor burden and worse survival [ 22 ].

While the Kaplan–Meier survival curves still demonstrated significantly better overall survival and disease-free survival for the “T3 single” group ( Supplementary Figures S1–S3 ), the difference in cancer-specific survival became less pronounced, although the curves still showed a trend towards better survival in the “T3 single” group.

However, we observed an unfavorable trend of decreasing lymphadenectomy quality over the years.

There is a strong trend of a direct correlation between adenocarcinoma (faceted square) and large cell carcinoma (triangle) and a highly significant inverse correlation with NSLC at the upper end (pentagram) and small cell cancer (rectangle) at the lower end ( Table 3 ).

However, it is noteworthy that there was a positive trend favoring low zonulin expression regarding PFS.

Importantly, our results demonstrate a worrying trend of early recurrences, most within 100 days of induction therapy and identified on the first post-induction surveillance cystoscopy, among patients receiving reduced-dose induction BCG.

CA 19-9 36 U/mL had marginal significance as a prognostic factor.

It should be noted, however, that all studies consistently reported a nonsignificant trend toward a lower risk of non-response to therapy for carriers of tumor MSI-H status. 3.3.2.

However, there was a significant trend in etiology between these three groups.

Both patients with increased zonulin expression in the tumor sample ( Figure 2 A) and those with higher serum levels ( Figure 2 B) demonstrated a clear trend with a worse PFS.

With respect to pre- and post-GVHD onset differences, the number of datapoints was not sufficient for a statistical trend analysis.

crizotinib) and in DoR (entrectinib only, due to non-reporting for crizotinib) showed a trend toward more favorable outcomes with repotrectinib.

Although NNMT1 was modulated in two tumor types, the differential expression was highly significant in LuSCC.

According to the Institute of Health Information and Statistics of the Czech Republic, about 3,000,000 transabdominal ultrasound investigations are performed in the Czech Republic per year, with a slightly increasing trend within the past five years (from 2,829,511 in 2018 to 3,109,057 in 2022) [ 147 ].

Kendall’s W concordance coefficient exceeded 0.85 for all measures, with corresponding p -values below 1 × 10 −12 , indicating highly significant agreement.

Notably, SOCS1 gene expression showed a highly significant inverse correlation with GCLC gene expression ( Figure 5 C).

The DOS regimen demonstrated better pathological response and showed a trend toward longer 3-year progression-free survival and 3-year overall survival, with a comparable safety profile to the SOX regimen [ 61 ].

The exploration of tumour size categories revealed a highly significant variance in malignancy probability, with the most notable contrast emerging between the initial size category (tumours measuring 10 mm or less) and the subsequent size intervals.

Whilst BMI was strongly associated with an increased risk of BMI-related cancers in our analysis, we still found an increasing trend of BMI-related cancers, even after adjusting for BMI in our regression models.

Patients who had preoperative plus postoperative radiotherapy showed a trend toward superior local control.