“a slightly increasing trend”

In the domains of “Care” and “Communication”, Phase 3 showed only a slightly increasing trend that was significantly lower in Phase 3 compared with Phase 1 (change in slope −0.05 with p = 0006, and −0.03 with p = 0.027, respectively).

Furthermore, anal cancer highlighted a Joinpoint with a decreasing trend from 2008 to 2014 (APC = −3.7%, 95% CI = −4.7, −2.8; p < 0.001) and a slightly increasing trend in the period 2014–2018 (APC = 1.3% 95% CI = −0.6, 3.3; p = 0.136).

ow–stable depression and low–stable anxiety group” (I dep = 1.293, p < 0.001, I anx = 1.744, p < 0.001, S dep = 0.029, p = 0.344, S anx = −0.135, p = 0.03); class 3 included 26% of pregnant women (n = 275) with moderate initial levels of depression and anxiety, and a decreasing trend in anxiety and a slightly increasing trend in depression, named “moderate–slightly increasing depression and moderate–decreasing anxiety group” (I dep = 6.925, p < 0.001, I anx = 5.804, p < 0.001, S dep = 0.144, p = 0.375, S anx = −0.769, p < 0.001).

Total SARS-CoV-2 IgG antibody levels first increased after vaccination with the third dose ( P < 0.001; paired Wilcoxon test; Figure 2 A) and then were stable with a slightly increasing trend during the 12-mo follow-up ( P < 0.001; Figure 2 A).

Furthermore, the RTs in correct trials showed a slightly increasing trend with task difficulty (mixed effect linear regression, β = –0.021 c , p = 0.001), while the effect on the incorrect RT became less prominent than for the fixed-delay group (mixed effect linear regression, β = –0.046 d , p = 0.014).

Among residents in ALFs, the ARS score showed a slightly increasing trend during 2007–2017 for the whole cohort ( p < 0.001 for years).

Before the implementation of the policies, the consumption of oral PPIs exhibited a slightly increasing trend (β 0 = 0.14, p < 0.001).

In the younger group with T1D aged 14–17 years, the proportion of smokers was 6.4% in 2016 and 8.3% in 2023 after adjusting for sex, migration background, diabetes duration and taking repeated measurements into account, with a slightly increasing trend (relative increase: 2.86%, CI 1.21–4.55 per year, p < 0.001).

There was a slightly decreasing trend for hospital A (Spearman’s rho = −0.11, p < 0.001) and hospital B (Spearman’s rho = −0.10, p < 0.001), while a slightly increasing trend for hospital C (Spearman’s rho = 0.16, p < 0.001) (Fig. 1 ).

The average consumption of ciprofloxacin showed a decreasing trend (−0.4 DDD per 1000 OBD per month, p = 0.002), while the average consumption of macrolide antibiotics, betalactamase stable penicillins, and piperacillin-tazobactam showed a slightly increasing trend ( Table 2 ).

There was a slightly increasing trend in serum A1M levels ( P = 0.003) but with no significant difference from baseline at any time point by post hoc tests, suggesting that molecules around this size could not be removed by hemodialysis ( Fig 2 C).

For non-ESBL-EC BSIs, the 30-day case-fatality rate varied from 8.7% in 2018 to 11.0% in 2022 with a slightly increasing trend (AAI: 3.0%; 95% CI: 0.9 to 5.1%; p < 0.01) ( Figure 1B ).

Regarding psychological distress, there was a slightly increasing trend in K6 scores across the COVID‐19 survey waves, with a small effect size, F (1.97, 2537.12) = 16.47, p < 0.01, η 2 = 0.003.

The NTI values also showed a slightly increasing trend with the latitude ( r = 0.53, P = 0.01; Fig. 5a ), suggesting a stronger environmental filtering effect in the polar regions.

After the policy intervention had been implemented, the constituent ratio of inpatients outside the county changed significantly and showed a slightly increasing trend (0.27, 95%CI: 0.12 to 0.42, p–value < 0.01).

The temperature at 30 m depth in the Sound shows a slightly increasing trend during the period 1997–2022 (Kendall’s tau = 0.072, p = 0.015, n = 554).

A fluctuation in IMR was observed for post-neonatal births, with a slightly increasing trend (p=0.02) (Figure 2 ).

Overall analysis of all-cause cirrhosis-related mortality Before the pandemic, prior to 4/2020, there was a slightly increasing trend in cirrhosis-related mortality per 100,000 persons overall at a semiannual percentage change (SAPC) of 0.54% (95% CI 0.0–1.0%, p =0.036), with seasonal variation ( Fig. 1A, B and Table 2 ).

There was no temporal trend in the proportion of late HIV diagnoses (relative risk (RR) 1.008, 95% CI: 0.997–1.020, p = 0.159), whereas we observed a slightly increasing trend in the proportion of very late diagnoses (RR 1.017, 95% CI: 1.00–1.03, p = 0.037).

pylori -related PUD exhibited a decreasing trend after 2014 ( P = 0.01 for trend), and drug-related PUD showed a slightly increasing trend in the past 10 years ( P = 0.04 for trend).

The YLLs of road injuries decreased annually ( P < 0.001), whereas self-harm exhibited a slightly increasing trend ( P = 0.041).

A slightly increasing trend in the percentage of women with plasma stages was observed in BioFINDER-2 ( P = 0.047), which was not significant in TRIAD ( P = 0.063) (Extended Data Fig. 5 ).

At each storage temperature, there was a slightly increasing trend from the first month without significant differences ( p > 0.05) ( Table 2 ).

A slightly increasing trend for platelet adhesion was observed, but only the number of thrombi at 1600 s −1 reached statistical significance ( p < 0.05), going from 63 ± 83 to 126 ± 111 for WB and WB + PDMP, respectively.

The beta value in the MFG2 had a slightly increasing trend, which was not statistically significant ( p > 0.05).