Excerpts

Earlier year of surgery did not reach statistical significance on the α = 0.050 level in univariable analysis but showed a trend towards shorter OS ( p = 0.064) and was therefore included in the multivariable analysis.

The PTR group showed a trend for longer OS (20.5 versus 16.0 months, p = 0.064) but was not related to OS in Cox regression multivariate analysis ( p = 0.220).

Among the genes with the most pronounced up-regulation in both OVCAR-3 and SKOV-3 cells, MX1 gene only showed a trend towards prolonged OS (HR = 0.76, p = 0.064), just like IFI44L (HR = 0.79, p = 0.092).

Under criterion 2, age approached significance ( p = 0.064). 3.2.

We also observed that the non-expression of CD133 showed a trend to worse OS ( p = 0.064) ( Figure 12 a).

Age, which only showed a trend toward significance ( p = 0.064), was selected nine times, and nodal status was selected five times as well.

Although located in the intron region where its function was not obvious, rs7165790 was identified as borderline significant in expression quantitative trait locus (eQTL) relationship with BLM ( p = 0.0644).

The association between this SNP and nausea was marginally significant in the dominant model ( p = 0.0645), but no significant associations were found in the other analyses ( Table 5 ).

These relapses had an effect on mice survival ( Figure 5 C): the cetuximab/rapamycin combination was found to result in longer survival compared to the cetuximab/rapamycin/irradiation (close-to-significant difference: p = 0.0648) and to the cetuximab/irradiation (significant difference: p = 0.0015) regimens. 3.

A similar trend was found in U-251MG; however, TRAM-34′s effect in NSC medium did not quite reach statistical significance (see Figure 9 B,C; p = 0.0649).

A trend towards significance was observed with a higher amplitude of N75 in patients with no preoperative VF deficit— p = 0.065 ( Supplementary Material Table S1 ).

On the other hand, preoperative prealbumin ≥ 275 mg/mL (shown to influence survival up to 7 years [ 32 ] in an independent manner) was also associated with a slight trend (non-significant) toward better survival ( p = 0.065) ( Figure 2 (G2)).

Despite the numerous associations of SARIFA with a poor prognosis, significant association of SARIFA with colon-cancer-specific survival ( p = 0.008) could be solely demonstrated in group A, whereas group B only exhibited a trend toward significance ( p = 0.065).

As a result, and as indicated in Figure 1 J, the TRAM-34-mediated depolarization of the membrane potential differed almost significantly (p = 0.065, n = 4 pairwise comparison) between irradiated WT and K Ca 3.1 KO cells ( Figure 1 J).

A recent meta-analysis examining the association between cannabis use and cancer incidence in the United States showed a trend towards a lower risk of cancer among cannabis users, with an overall risk of 0.90 ( p = 0.065), which became statistically significant (0.86; p < 0.025) after removing the data on testicular cancer, which showed an increased risk [ 142 ].

Moreover, in the original eCura system, SM2 or SM3 tumors also were not independent risk factors for lymph node metastasis after non-curative ESD, but had marginal significance ( p = 0.065).

High MYC expression showed a trend toward worse survival (HR 2.60, 95% CI 0.94–7.15, p = 0.065).

The hemorrhage–depth interaction approached significance ( p = 0.065), suggesting attenuation of depth-related PTX risk.

However, a nonsignificant trend towards an increased intratumoral TOX count was noted in early-stage sCRC ( p = 0.065, as depicted in Figure 4 D).

After the inclusion of the MDS-CI as a categorical variable (reference group: low-risk) in a model with a dichotomized DIPSS, the MDS-CI high-risk category retained its independent prognostic value (HR 14.64; 95% CI 4.42–48.48; p < 0.001), whereas for the MDS-CI intermediate-risk category, the prognostic impact was only of borderline significance (HR 1.97; 95% CI 0.96–4.03; p = 0.065; see Table 2 ).

The association between pT stage and vocal palsy persisted as a nonsignificant trend (OR ≈ 1.55, p = 0.065), suggesting a possible gradient of risk without definitive statistical support.

On multivariate analysis, treatment with CRT showed a trend toward significance for LRC (HR = 2.23, 95% CI 0.95–5.23, p = 0.065).

Accordingly, we reported that patients having a PSA DT ≥ 6 months present a significantly lower number of lesions compared to those having a faster rise in PSA levels after primary treatment; we observed the same trend on a patient-based analysis, although after adjustment for multiple testing, the p -value only approached the level of significance ( p = 0.065).

SHI fell slightly short of significance (HR: 1.49, 95% CI: 0.98–2.28, p = 0.065) in the multivariate analysis.

The location of metastatic lymph nodes was borderline significant ( p = 0.065).