Excerpts

First, our data demonstrated anti-EGFR re-exposure to be associated with a distinctly higher OS, although only with borderline significance ( p = 0.06), and high response rates to retreatment.

PI3K protein expression was increased by AET in the WT+TR (30%, p = 0.02; Figure 9 B) group and also there was a strong trend to increase mTOR expression (87%, p = 0.06; Figure 9 D) compared with WT (100%).

Although not statistically significant, patients with recurrent disease showed a trend toward longer OS and PFS than those with unresectable disease (OS, p = 0.06; PFS, p = 0.05) ( Figure 2 ).

A positive trend near statistical significance was also found for a lower N/L ratio ( p = 0.06).

There was an observed trend towards longer operative time for the MIS-ILND approach (mean difference 28 min; 95% CI −2 to 58 min, p = 0.06), particularly with the robotic-assisted technique.

There was no significant variable to predict major revision, although the administration of perioperative chemotherapy was a marginally significant variable ( p = 0.06).

In our study, pCR was an independent prognostic factor of longer DFS and almost significant for OS ( p = 0.06).

However, patients without a CDKN2A deletion/mutation or CDK4 amplification had nearly statistically significant, longer OS compared to patients with a CDKN2A deletion/mutation or CDK4 amplification (17.6 versus 10.1 months, Figure 3 , p = 0.06).

The distance from the SMF to the upper tumor margin presented marginal significance for predicting FNI ( p = 0.060, Table 2 ).

Similar to the trend we observed in tumor-derived SUV max , SUV max in post-surgical scarring also showed a trend towards a positive correlation with myocardial tracer uptake (Pearson’s r = 0.49, p = 0.06) Otherwise, there were no significant correlations between radiotracer uptake in normal organs and post-surgical scarring ( Table S2 ). 3.5.

10 min) showed a marginal trend for CVAEs ( p = 0.06) [ 23 ].

Patients holding an SUV max above this value exhibited a statistical trend toward a longer median PFS (52.0 versus 18.7 months; p = 0.06), Figure 4 .

A previous finding of higher SST5 mRNA levels in gsp - tumors had been described with borderline significance ( p = 0.06) by our group [ 9 ].

ER+ cancers demonstrated a strong trend towards fewer total CD8 + T cells as compared to ER− disease ( p = 0.06; Figure 4 a).

A nearly significant lower presence of ctDNA DDR gene mutations was found in non-smokers compared with ever-smokers ( p = 0.06) in the 3-gene subset analysis.

SMI and GS also increased, but were only borderline significant ( p = 0.06).

did not find a low PMI to be a statistically significant independent risk factor for OS, although a statistical trend was shown (HR 1.59; 95% CI 0.98–2.59; p = 0.06) [ 35 ].

The mGPS was a marginally significant variable ( p = 0.06).

A significant association was demonstrated between expression of UBC and pT status ( p = 0.0098), and a marginally significant association was observed between UBC expression and Gleason score ( p = 0.060).

Multivariate Cox proportional hazards regression analysis adjusting for PS, pTNM stage, tumour size and nodular involvement revealed that lower PHD1 mRNA expression in the primary tumour had borderline significance for shorter OS (HR = 0.908; 95% CI: 0.822–1.004; p = 0.06) ( Table 4 ). 4.

In the radiomics model, wavelet.LHL_glcm_Correlation emerged as a marginally significant predictor (HR = 2.09, 95% CI: 2.59–98.60, p = 0.06), suggesting its potential relevance in survival prediction and underscoring the value of texture-based imaging features in capturing tumor characteristics.

The radiomics feature original_shape_Elongation demonstrated a trend towards significance (HR = 0.45, 95% CI: 0.2–1.03, p = 0.06), potentially indicating a protective effect.

Moreover, H 2 O 2 generation in DTCs showed a trend toward a correlation with extrathyroidal extension ( p = 0.06) ( Figure 3 ). 3.4.

Smoking was 16.5% more frequent in the immunotherapy + cannabis (56.9%) group than the immunotherapy-only group (40.4%), but this difference was not quite significant (χ 2 (1) = 3.512, p = 0.0609, Figure 1 B). 3.2.

Adding the loss of expression of CDX2 to the multivariate model showed it to have a tendency toward significance as increased risk of death (HR = 2.74, 95% CI (0.96–7.84), p = 0.061), and it was statistically significant for risk of death or relapse (HR = 2.77, 95% CI (1.06–7.23), p = 0.037). 3.2.