The overall improvement of ODI and SRS-30 compared to baseline was similar in both groups (all p > 0.05), however the ERF group showed a trend toward lower improvement of ODI at 1-year postoperatively (17.3 vs 24.6, p = 0.051).
Age showed a trend-level effect (HR 0.96, 95% CI 0.92–1.00, p = 0.051) (Table 2 ).
On the other hand, JAG1 gene SNPs rs2235811 and rs2275811 showed a trend to association with FN-BMD and LS-BMD ( p = 0.051 and 0.089, respectively); well above the multiple test-significance threshold estimated at 0.009.
Clinical Correlation The GMV alteration in the right putamen significantly positively correlated with the HAM-A score ( r = 0.44, p < 0.05; Figure 1B ), while the GMV alteration in the left IPL showed a trend to was negatively correlated with the HAM-A scores ( r = −0.39, p = 0.051; Figure 1C ).
CTCAE toxicity grade before O 3 T was inversely correlated with time-lapse between the end of radiotherapy and rectal bleeding (rho = −0.588, p = 0.044) and showed a trend towards a borderline significant direct correlation with O 3 T duration (rho = 0.574, p = 0.051) and number of rectal O 3 T sessions (rho = 0.648, p = 0.059); that is, higher toxicity grade was related to earlier commencement of RB and longer treatment with O 3 T.
Accordingly, diffusivity differences in the superior cerebellar peduncle (SCP) showed a trend with tool use (ASD group, AD: p = 0.051), supporting the notion that alterations of the SCP may be related to motor deficits rather than clinical group membership, in contrast to the decreased diffusivities of the middle cerebellar peduncle, which may be more related to autism core symptomatology.
The decrease was statistically significant in the LFD group ( p = 0.002), while the traditional IBS diet group showed a trend toward improvement ( p = 0.051).
Although the difference did not reach statistical significance, bevacizumab showed a trend toward improved survival (p=0.051, Figure 5B ).
FGF21 showed a trend ( p = 0.051) in overall change in participants following the LCHF diet after decreasing from a median (IQR) of 148.16 (203.49) to 99.4 (92.43) pg/mL at week 4 and increasing again to 167.38 (152.08) pg/mL at week 8, with post-hoc analysis reporting a trend ( p = 0.069) between baseline and week 4, whereas no change was observed in HCLF.
IL-6 and CRP were positively associated with high nuclease activity of isolates ( P < 0.001 and P = 0.049, respectively), while S100A8/9 showed a trend ( P = 0.051) indicating that in inflamed airways, S. aureus isolates with high nuclease are selected, thereby presumably facilitating escape from NETs ( 18 , 19 ).
The interaction term group × direction showed a trend (p = .051, using Pillai’s trace V = .337, F(4,22) = 2.80).
A significant difference in reversal learning was found across groups (day 2, H (5) = 13.506, p = 0.019), as the adult offspring of Poly I:C rats showed a trend towards rapid reversal (post hoc p = 0.051), indicative of excessive switching behavior, which was significantly improved following prenatal exposure to omega-3 PUFAs (post hoc p = 0.045) ( Figure 4 B and Table S2 in Supplementary Materials ).
By univariate survival analyses of all cases, high expression of CD47 alone showed a trend of association with reduced RFS ( p = 0.051; Figure 2A ).
5571 ± 3524 ms 2 /Hz, p = 0.002) and showed a trend toward higher values during SSM (58,941 ± 91,929 ms 2 /Hz, p = 0.051).
As a consequence, the estimated incidence of treatment failure showed a trend to being higher in the everolimus than in the control group (53.2% versus 25.0%, log rank p = 0.051) ( Fig 4 ) ( Table 6 ).
Participants with gallbladder polyps showed a trend toward a higher prevalence of colorectal adenoma than those without gallbladder polyps (52.7% vs. 39.2%, P =0.051).
Type 1 MNV showed a trend ( p =0.051) towards smaller probability for the correct detection compared to all other subtypes.
Chi-square (χ 2 ) tests revealed that low ALC was significantly associated with a high EBV-DNA load ( p = 0.040), and showed a trend towards correlation with B symptoms ( p = 0.051) (Table 2 ).
Although the prevalence of cystoid macular edema showed a trend toward differences between the FAF group, this did not reach statistical significance ( p = 0.051).
We further observed that plasma levels of acetic acids correlated with IFN-γ (ρ = 0.301, p = 0.003) and showed a trend with TNF-α (ρ = 0.197, p = 0.051); plasma levels of butyric acids tended to correlate with IFN-γ (ρ = 0.194, p = 0.06) (eFigure 2).
Participants did not increase positive affect after compared to before the experiment ( Figure 2 A, Table S1 ; PANAS-P, before: 56.4 ± 12.4, after: 56.7 ± 13.4, paired one-tailed t-test, t 19 = 0.13, p = 0.89), but showed a trend decrease in negative affect (PANAS-N, before: 20.5 ± 3.1, after: 19.4 ± 2.3, paired one-tailed t-test, t 19 = 1.72, p = 0.051).
In the CAD cohort with a 2-year follow up, LDL-C levels measured within the last 3 months of follow up were significantly associated with an increased risk of BARC criteria 3 to 5 grade bleeding (P < 0.001) and showed a trend toward an increased risk of ICH (P = 0.051).
Alcohol use showed a trend toward higher risk that did not reach statistical significance (OR 1.88, 95% CI 1.00–3.55; p = 0.051).
On the other hand, when AD converters were analyzed in comparison with MCI/non‐AD subjects, a former or current smoking habit showed a trend to be a relatively protective factor for the progression to AD ( p = 0.051), even considering only a small cohort of individuals.
However, the frequency of HIV-1 inter-subtype recombinant viruses in the HIV-1 pol gene (26.7%) showed a trend to be higher (p = 0.051; Fisher exact test) than the frequency observed in the HIV-1 env gene (8.6%) in the same population [21] .