“showed a trend”

As shown in the forest plot ( Figure 5B ), the EGFR subgroup showed a trend toward improved OS (pooled HR =0.82, 95% CI: 0.63–1.06), and Gem-Nimot achieved a significant improvement in PFS (HR =0.61, 95% CI: 0.37–0.99) ( 30 , 31 ).

Within SCC cases, PD-L1–positive tumors showed a trend toward increased CD8 + T-cell infiltration compared with PD-L1–negative tumors, although this difference did not reach statistical significance ( P = 0.063; Fig. 3G ).

Sarcoma patients with high expression of IMPDH2 showed a trend towards poorer overall survival.

The FIB-4 index correlated positively with worsening episodes ( p < 0.0001), and the CA125 value showed a trend with mortality.

Univariate Cox regression identified Bachmann’s bundle ablation as significantly protective against recurrence (HR 0.40, 95% CI 0.18–0.88, p = 0.024), while larger LA diameter showed a trend toward higher recurrence.

While both the active sunflower lecithin group and the placebo group showed a trend towards improved dry eye symptoms as measured by the SPEED questionnaire (Figure 1 ), statistical significance was not present in either group.

Although CD4 + T cells showed a trend toward increased infiltration, this change was not statistically significant (Fig. 6 k).

Although relevant data were lacking in many studies, particularly with regard to AEs, the pooled analysis showed a trend toward more AEs in peroral compared to peranal MSEs (6.1% [95%‐CI: 3.1%–11.8%] vs. 3.2% [95%‐CI: 1.6%–6.2%] but similar rates of SAE (1.7% [95%‐CI: 1.1%–2.5%] vs. 1.3% [95%‐CI: 0.6%–2.6%]).

All Aipysurus species sampled showed a trend towards lighter colour patterns in WA Coast populations compared with those from the Timor Sea (Figs. 6 – 7 ).

The PNMR estimated by the wealth quintiles 3 (Table 3 ) showed a trend of being the lowest in the highest wealth quintile (the richest 20% of households in the sample) and highest in the lowest wealth quintile (the poorest 20% of households in the sample).

Consistently, A20-C3G-Y564H cells showed a trend toward reduced levels of the anti-apoptotic protein Bcl-xL compared to control cells (Fig. 3 G).

Similarly, the pathological response showed a trend toward a higher high-response rate in the rectal group compared to the gastric group (49.0% vs. 32.5%), but without reaching statistical significance ( P = 0.057).

Inhibition of TLR4 significantly reversed the M1 EV -induced upregulation of IL1B and showed a trend toward reduced CXCL8 expression, whereas the other receptor inhibitors or antagonists had no effect on the M1 EV -induced upregulation of CXCL8 or IL1B (Fig. 4 B).

While rt-PA showed a trend toward higher reperfusion rates, this did not translate to clinical benefit.

ARID(1A/1B/2)- mut patients showed a trend toward shorter OS than that observed for SWI/SNF-wt patients among 66 STK11 wt KEAP1 wt KRAS mut NSCLC patients (12.2 vs. 29.9 months, HR = 2.20 [95% CI 0.98–4.91], P = 0.052; Additional file 1: Fig.

Additonally, ADMSCs co-cultured with chondrocytes showed a trend of chondrocyte differentiation, and chondroid structure formation occurred post-transplantation in vivo after the co-cultured mixed cells were inoculated into tracheal scaffolds [ 89 ].

All clinical outcomes showed a trend towards larger improvements in the exercise and protein arm, but these were not statistically significant.

Lack of awareness regarding proper medication use was significantly associated with a 6.5‐fold increased risk of polypharmacy (AOR: 6.48; 95% CI: 1.39–30.16; p = 0.017), whereas lack of awareness about medication side effects showed a trend toward increased risk, although this was not statistically significant (AOR: 1.98; 95% CI: 0.96–4.08; p = 0.061).

Additionally, Caco-2 cells with anxa6 knockout and transfected with pEGFP-EspF showed a trend toward increased LDH release compared to V2 cells transfected with pEGFP-EspF alone ( Figure 6E ), suggesting a potential additive effect of ANXA6 deficiency and EspF expression on cellular damage.

Overall, while the PA group had significantly shorter anastomosis times, the SA group showed a trend toward superior renal recovery, with no significant difference in complications between the two approaches.

While the WeChat-BHC health counseling program showed a trend toward reducing depression symptoms, it did not create a statistically significant difference compared to TAU.

While the dupilumab group showed a trend toward more frequent severe conjunctivitis and ophthalmologic referrals, none of these differences reached statistical significance.

Although a high expression of miR-106b-5p showed a trend towards shortened overall survival in GC patients, this association did not achieve statistical significance.

National Natural Science Foundation of China 10.13039/501100001809 81600094 81970114 The percentage of T cells in lymphocytes was 78.6% ± 7.8% versus 74.0% ± 5.4% in pediatric AA patients versus the controls ( p = .015) and showed a trend of increase with disease severity (Figure 2A ).

In this study, the annual rates of any and severe AE showed a trend: highest for patients with MVD, followed by those with RVD and OVD, and the lowest for the normal group.