Barely Significant
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“showed a trend”

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In the literature

Although there was no statistical significance when comparing mean scores at week 6 or week 12 of intervention, reductions in the total mean score of MENQOL (decreased symptoms of menopause) at each visit compared with baseline subsequently showed a trend of improved QOL among participants by the end of the study.
Tafamidis showed the greatest relative reduction in the occurrence of the primary outcome as compared to placebo (HR 0.69, 95% CrI from 0.53 to 0.88), followed by vutrisiran monotherapy (HR 0.74, 95% CrI from 0.58 to 0.91); acoramidis showed a trend towards benefit as compared to placebo (HR 0.76, 95% CrI from 0.56 to 1.03).