Furthermore, our study suggested that TNBC patients receiving immunotherapy combined with chemotherapy showed a trend towards pCR increase in the gHRR mutation group, although the difference was not statistically significant.
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The lactic acid content in ensiled ATMR control (ATMR-C) showed a trend from increase to decline, whereas in other treatments, lactic acid content decreased immediately when the samples were exposed to air.
Similarly, in Phase 2, RF-positive patients showed a trend toward lower flare-free population rates compared with RF-negative patients; however, the difference was not statistically significant (Fig. 2 E).
In contrast, higher interferon/antibody-related gene expression showed a trend toward better survival.
Left ventricular ejection fraction (LVEF) showed a trend toward an inverse association with CMD (OR = 0.969; 95% CI: 0.938−1.002).
4 Discussion In this study, older patients with a low CCR showed a trend toward a higher risk of 3‐month post‐discharge mortality.
In the present study, BRPC with an arterial contact angle of ≥ 90° was significantly associated with R1 resection and showed a trend toward increased local recurrence after resection.
In univariable analysis, patients with MGFA class I prior to surgery were significantly more likely to achieve favorable outcomes ( p = 0.042, OR = 2.10, 95% CI: 1.03–4.40, see Table 3 ), whereas those with MGFA class III–V showed a trend toward lower remission rates, although without statistical significance.
Exploratory analyses of patients with classic T1DM and severe DKA showed a trend toward shorter time to resolution, although the difference did not reach statistical significance.
While no statistically significant difference was observed in the cumulative recurrence rates between the GCs group and the GCs + EBD group at the 1 st, 3rd, 6th, and 12th months after treatment ( P = 0.36, 0.96, 0.78, and 0.28, respectively), the GCs + EBD group showed a trend toward lower recurrence rates at all these time points.
Consensus clustering of immune cell proportions classified BCa samples into four distinct subtypes (C1-C4), with differential risk group distributions: C1 (wound healing), C3 (inflammatory), and C4 (lymphocyte-depleted) subtypes were relatively more common in low-risk cases, while the C2 (IFN-γ-dominant) subtype showed a trend toward higher prevalence in high-risk patients, though this association did not reach statistical significance (Fig. 4 E).
Patients who became resectable after conversion therapy showed a trend toward improved survival.
Among patients with multiple lesions, SRS showed a trend toward improved survival relative to WBRT and craniotomy, although without statistical significance.
Even though we employed very conservative assumptions, these sensitivity analyses still showed a trend of higher preeclampsia knowledge score difference in those receiving the intervention.
1 B∼ 1 F, it can be seen that the yield of WFM showed a trend of increasing and then decreasing with the increase of the NaOH concentration, ultrasonic power, ultrasonic time, solid-liquid ratio and ultrasonic temperature ( P < 0.05).
In the deep brain regions, where IT delivery has struggled to demonstrate significant RNA KD in other large animal models, 9 , 11 ICV delivery resulted in significantly enhanced KD in the caudate and showed a trend toward more KD in the thalamus that did not reach statistical significance ( Figure 7 B).
The integration of the risk model constructed by HGRGs yielded a numerically higher, but not statistically significant, C-index (0.769, 95% CI: 0.734–0.804) and showed a trend toward improved discriminative ability versus omitting it (C-index = 0.759, 95% CI: 0.723–0.795) ( Figure 7d and e ). 3.5 Enrichment analysis KEGG enrichment analysis identified several functions associated with the five HGRGs, including glycolysis/gluconeogenesis, carbon metabolism, etc.
Patients with CCUS-like ( P = .01) and SF3B1 ( P < .0001) were less likely to be treated with HMA or more intensive therapies, whereas those with bi-TET2 ( P = .09) and del5q ( P = .06) showed a trend toward being treated less often with HMA or intensive therapies.
Regarding further modification to enhance nuclease resistance, incorporating phosphorothioate (PS) modifications to all bases of DBCO-RNA/DNA in RGG/DGG showed a trend towards increased RNA imaging efficiency, although the difference was not statistically significant.
Hypoxic-ischemic encephalopathy (HIE) showed a trend toward higher prevalence in the ROP group but was not statistically significant (70.59% vs. 55.02%; P=0.06).
Compared with those indicators before treatment, they showed a trend of improvement ( Table 8 ).
Although each showed a trend toward lower mortality rates with AMD, the meta-analysis indicated that NIF and AMD may result in little to no difference in short-term deaths, with substantial uncertainty.
There was no significant effect of consumption amount ( F 1,148 = 2.61, p = 0.11), although consumption showed a trend where it increased up to 0.001% and was the lowest at 0.10% (Figure S2 ).
Lathosterol showed a trend toward greater lowering in patients with higher LDL-C at baseline, and the XR 0.8 mg/day group was associated with significantly greater lathosterol lowering than the IR 0.2 mg/day group, with the exception of the LDL-C ≥ 160 mg/dL subgroup. β-Sitosterol and campesterol showed a trend toward greater lowering in patients with higher LDL-C at baseline, but there was no statistical difference in the percentage change among the treatment groups.
The results showed a trend of improvement in cognitive function following mind–body exercise interventions, but the effect was not statistically significant.