“showed a trend”

IL10 - B cells also showed a trend of IgM downmodulation and increased CD5 expression, albeit substantially less than IL10 + B cells ( S4B Fig ).

10 , 11 Immunohistochemical staining of F4/80 + macrophages in the liver did not show a significant difference in macrophage numbers between conditions, although it showed a trend toward decreased F4/80 + cells ( Figures 3 A, A7 ).

Further analysis of the effect of immunosuppressant therapy on long-term prognoses showed a trend towards better outcomes in the GC group than in the non-GC group.

In this study, the immunophenotyping of the monocyte subsets in our patients showed a trend toward an increased level of intermediate and non-classical monocytes (CD16+).

However, although the adjusted relative risk and Kaplan-Meier estimates showed a trend towards reducing AOM with OMT, there was no statistically significant effect.

Discussion This study demonstrated that NSCLC patients with prior CIP had comparable transition rates to second-line therapy but showed a trend toward shorter OS and experienced a higher incidence of drug-induced pneumonitis with DTX-based regimens.

In patients treated with biologic therapies and with suboptimal disease control, no conclusive agreement was achieved, although the median results showed a trend towards AIT prescription in these profiles ( Table 3 ).

For males, in addition to the increasing trend from 2005 to 2010 [APC = 1.31 (95% CI: 1.24, 1.38)], all showed a trend of decline in the rest of the years.

When the working face advanced to 200 m (near the railway), mining operations were suspended for a period, and the surface showed a trend of lifting due to advance grouting, with a maximum lift of less than 100 mm.

Aromatase inhibitors monotherapy (OR 2.05; 95% CI: 0.31–16.54) and tamoxifen with LHRH agonists (OR 1.25; 95% CI: 0.14–11.05) also showed a trend toward increased risk of PCIA, but these associations were not significant.

20%, p = 0.058) showed a trend toward higher rates in the open group, although these differences did not reach statistical significance.

2 , 3 , 4 , 5 The largest long-term trial of aspirin after myocardial infarction, the Aspirin Myocardial Infarction Study ( Figure 1 ), showed a trend to harm (increased mortality) rather than benefit, 5 the authors concluding: “aspirin is not recommended for routine use in patients who have survived a myocardial infarction.” The PARIS-II (Persantine-Aspirin Reinfarction Study Part II) was the second largest, long-term, placebo-controlled trial of an antiplatelet regimen after myocardial infarction ( Figure 1 ).

A lower level of education showed a trend toward association with persistent fatigue, but this did not reach statistical significance.

This combination therapy showed a trend of superior efficacy in the imatinib‐sensitive group [ 81 ]. mTOR is central in regulating cell growth and proliferation, and it plays a key role in angiogenesis [ 82 ].

Kaplan-Meier survival analysis showed a trend toward prolonged survival in the MSLN-1 F-NK group compared to 1 F-NKs, though the p-value did not reach statistical significance ( p = 0.0625) (Fig. 6 G).

However, when NK-92 + shB7-H6 was compared with NK-92 + shNC, the rate of NK-92 cells secreting PFP showed a trend corresponding to that of B7-H6.

Our study showed a trend towards rounding in half and whole centimetres in large tumours, but the relatively low frequency of carcinomas with a diameter of 1.0 and 2.0 cm suggests that rounding to whole centimetres was avoided in small tumours (1.0 and 2.0 cm).

The multivariate logistic regression model also showed a trend toward an increased incidence of postoperative infection, although this was not statistically significant (odds ratio [OR] = 5.4, P = 0.066).

Education level showed a trend, though the difference was not statistically significant (p = 0.063): there were more Shigella -positive cases among individuals with secondary education (19%) compared to those with higher education (6%).

Patients showed a trend toward better repigmentation response during the progressive stage compared to the stable stage.

Temporal trends in chlamydial infection-related disease burden from 1990 to 2021 Globally, case counts for incidence, prevalence, deaths, and DALYs showed a trend of initial increase, subsequent decrease, and final increase.

An analysis for the CD56 dim NK cell population was performed; patients with a high percentage showed a trend toward lower survival probability (log-rank HR = 2.436), but the difference was not statistically significant (log-rank p = 0.1831; 95% CI: 0.6553-9.055) (not shown).

lusitaniae were consistently enriched or showed a trend of enrichment in healthy controls across each dataset (Fig. 1d ), suggesting that these species may be potential markers of IBD-depleted gut fungi.

Although their results showed a trend in the expected direction, they did not find statistically significant differences in performance between individuals with tinnitus and controls.

The TIM-3 aptamer by itself enhanced T cell infiltration in the tumor and showed a trend of prolonged survival in mice; when combined with radiation therapy, it significantly increased median survival and produced some long-term survivors, an effect lost if T cells were depleted. 37 This indicates aptamers can function as immunotherapeutic agents, either alone or as adjuvants to standard treatments like radiotherapy.