However, in subgroups with squamous cell carcinoma (SCC), stage III disease, and PD‐L1 expression level subgroups (>50% and 1–49%), although OS and PFS showed a trend toward shortening in the severe group, the differences were not statistically significant.
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First, the link between situational awareness and missed nursing care showed a trend, but it was not statistically significant.
Still, the higher ICH rate and the higher mortality in the TNK group may be interpreted as a signal of harm, especially because the multivariate analysis showed a trend for the association of TNK with sICH and mortality when adjustment for EVT as a covariate was performed.
Besides, when Proseg was used for cell segmentation, SPICEiST showed a trend of superior performance compared to the SpaceFlow and GEX models, as represented by the median value.
Surgeon experience showed a trend, but not strong significance ( p = 0.13).
Specifically, the microglial soma size and branch complexity, which were initially altered by Prrc2a ablation, showed a trend toward normalization as development progressed.
Other comparisons also showed a trend toward smaller CPV in cases with a higher ALPS index.
Under the SSP245, SSP370, and SSP585 scenarios, MDN, MDD, MDS, and MDI broadly showed a trend of decreasing in the near- and medium-term, and increasing in the long-term.
Phage therapy showed a trend toward improved clinical scores, but this effect did not reach significance.
The PARP inhibitor ABT-888 (Veliparib) showed a trend toward increased activity, with case reports and early-phase studies suggesting that tumors harboring homologous recombination repair deficiencies, particularly BRCA2 alterations, may be more susceptible; however, evidence in prostate cancer remains limited ( 31 ).
We applied a log link function and a negative binomial distribution to the GLMMs, because the response variable showed a trend of overdispersion in a preliminary analysis that used the Poisson distribution.
The group of small (0–1500 μm 2 ) Mlc 1‐null astrocytes showed a trend towards lower F‐actin fluorescence levels (Figure 4E ).
Across all HOMA‐β quartiles, similar reductions in FPG were observed in the iGlarLixi and IDegAsp arms, while PPG reductions showed a trend towards being greater with iGlarLixi versus IDegAsp. 3.3.
Cohort analysis showed a trend of increasing risk until 1960 (RR = 1.000), followed by a marked reduction for more recent cohorts, such as 2010: RR = 0.056 (95%CI: 0.028 to 0.112).
In this model, slightly salty [AOR (95% CI): 0.71 (0.58–0.86)] and slightly bland [AOR (95% CI): 0.57 (0.45–0.72)] diets were significantly associated with lower SCA risk compared to normal salt preference, whereas very salty [AOR (95% CI): 1.14 (0.66–1.96)] and very bland [AOR (95% CI): 1.31 (0.80–2.16)] diets showed a trend toward increased risk, though without statistical significance in the latter two categories.
Individual and combined amino acid deprivation significantly enhanced or showed a trend to increase the eIF2α phosphorylation in MIA PaCa-2, HPAC, and SUIT-2 cells, indicating the activation of the GAAC pathway.
SF3B1 showed a trend of a higher overall frequency of CH variants in the Latino/Admixed American ancestry group compared to other ancestry groups.
In addition, the relative expression levels showed a trend of periodic upregulation and then down-regulation, whereas the expression trends of IKKα and IKKβ generally followed those of NF-кB ( Fig. 3A–H ).
In HPV-positive HNSCC, CHRAC1 and FXR1 showed a trend or were significantly associated with worse OS in univariate analysis ( Fig. 2E , Supplementary Fig. 8 ), with CHRAC1 remaining significant after multivariate analysis ( Fig. 2F , Supplementary Table 4 ), but not FXR1 .
The weight and estimated glomerular filtration rate showed a trend to increase over time, but these findings were not statistically significant for any of the outcomes.
Survival analysis was also performed based on VCAM1 level, but the result only showed a trend of poor prognosis for patients with higher VCAM1 level, which was not statistically significant ( Figure S1 ).
In the analysis, brigatinib monotherapy showed a trend toward lower mortality risk compared with alectinib monotherapy; however, this difference was not statistically significant in the multivariable analysis (HR, 0.69; 95% CI: 0.46–1.03; P=0.07).
8 The Indian RCT showed a trend towards increased survival that was not statistically significant, whereas the RCT done in the USA had no survival benefit.
16 showed a trend toward fewer AEs in the experimental group, only the former featured an IRR with a CI excluding the null.
Baseline serum Siglec-8 levels showed a trend toward better diagnostic performance compared to blood eosinophil counts for predicting 6- and 12-month clinical responses (area under the curve, 0.931 vs. 0.836; P = 0.08 for 6-month responders; and 0.811 vs. 0.628, P = 0.05 for 12-month excellent responders).