Barely Significant
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“showed a trend”

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The α-SMA fraction of the small and of the medium-sized arteries surrounding the GFM of AD subjects was significantly lower than that of their NDCTRL counterparts; the α-SMA fraction of arterioles surrounding the GFM showed a trend of being lower in the AD subjects than in the NDCTRL subjects (Fig. 2 a, right).
Although not statistically significant, MPA patients showed a trend towards an increased risk of thromboembolic events (pulmonary embolism: HR 1.16, 95% CI 1.01 -1.33; deep vein thrombosis: HR 1.17, 95% CI 1.03-1.32) and the risk of heart failure compared to GPA (HR 1.15, 95% 1.03-1.27) ( Figure 3 ).
Both CBD and GGT cases showed a trend towards elevated levels of all complement analytes compared to controls, but these were not significant with the exception of FI and Ba in CBD cases (FI, one‐way ANOVA; mean Cont: 0.118, CBD: 0.173, p = 0.0457; Ba, one‐way ANOVA; mean Cont: 0.184, CBD: 1.350, p = 0.035) (Figure 5, E, F ), and C3b/iC3b in GGT cases (one‐way ANOVA; mean Cont: 0.0044, GGT:0.0063, p = 0.0296).
Complement dysregulation in human tauopathies.
Brain Pathol · 2025 · PMC12488255
Supplementary data jnnp-2019-321758supp001.pdf In addition, for the entire group, HAM-D-17 ( F (1, 20.7)=13.7, p=0.001) and MADRS ( F (1, 20.7)=13.7, p=0.001) scores had significantly decreased over time from baseline until the end of the maintenance phase, whereas IDS-SR scores ( F (1, 20.7)=6.22, p=0.02) showed a trend towards decrease when measured throughout this period.