Barely Significant
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“showed a trend”

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did not reach statistical significancep = 0.05631.1× alphaplainly factual
Further intra-group analysis at 21 months stratified by infection status (N+ = infected, N− = uninfected) showed a trend toward higher IgM−/IgG+ MBCs induction in infected [N+] subjects compared to uninfected [N−] within the ChAd/BNT group, though this difference did not reach statistical significance ( p = 0.0563) ( Supplementary Figure S7A ).
The violin plots of marker expression at different passages showed (Figure 4G ) that the expression of the epithelial marker CD9 gradually decreased with culture passages, and the expression of CD326 showed a trend that first increased until passage P0 and then decreased with further culture passages, which was consistent with the trend of proliferation‐related genes (Figure 2H ).
Analysis of HRQoL using the SF‐12 showed a trend toward improvement in the intervention groups compared with the TAU group, both on the physical and mental scales.
Untreated responsive tumors (without ex vivo culture) also showed a trend toward expressing less IFN-responsive genes, especially the immunosuppressive enzymes IL4I1 and IDO1 induced by prolonged IFN exposure, but high interpatient variation prevented us from making statistical conclusions based on individual genes ( online supplemental figure S2B ).