“showed a trend”

The expression of SREBP-2 and its downstream target gene HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) showed a trend of inhibition in the MIX group ( Li et al., 2019 ).

Following initial tarlatamab infusion, patients with DLL3+ tumors showed a trend toward greater margination of peripheral T cells versus patients with DLL3−/unknown tumors ( Fig. 3B ).

Consistent with our hypothesis, adolescents who perceived higher levels of teacher unfairness compared to their peers, reported significantly increased depressive symptoms and showed a trend of poorer self-reported health in young adulthood.

UV-B irradiated Devic mice showed a trend toward reduced disease severity compared to nonirradiated controls ( SI Appendix , Fig.

Most categories showed a trend toward being pro-life or undecided, but it was not statistically significant. 48.2% of female doctors were pro-life versus 49.4% of men, while 3.5% of female respondents and 8.9% of men were pro-choice.

JPI-547 also showed a trend toward reducing β-catenin activation in AsPC-1 tumors in vivo , although the effect was not significant (p = 0.0791), likely due to limited sample size (Figure 4 E). qRT-PCR analyses confirmed that JPI-547 downregulated the expression of key target genes of the β-catenin pathway, Myc and AXIN2, specifically in PDAC cells with RNF43 mt (Figure 4 F).

Although pain at the natal cleft and general health compared to preoperatively were the only factors that reached a statistically significant difference between both groups, favoring the PG, other parameters analyzed in this study also showed a trend toward a favorable outcome in the PG.

Although bovine D/660 HEF and swine D/OK HEF exhibited similar replication kinetics, ferrets inoculated with the chimeric D/OK 660HEF virus showed a trend toward increased viral titers over time compared to those infected with swine D/OK.

Loperamide showed a trend toward longer drug survival than antispasmodics (log‐rank test 0.064) and bulking agents (log‐rank test 0.077).

Importantly, patients with elevated tubular CXCL12 expression showed a trend of accelerated deterioration of kidney function (referred to as kidney progression) ( Fig. 5D ).

Late LDX treatment showed a trend towards improvement in the mechanical and thermal PT with 1 week of LDX treatment and a significant improvement in these metrics after 4 weeks of LDX treatment (PT: STZ/VEH [18±10.56 g] vs.

Furthermore, During the 14-day post-discontinuation follow-up, key coagulation parameters (eg, aPTT, PT, TT, and Fib) of 70.2% TIC patients showed a trend toward normalization within 5 days after tigecycline discontinuation, which was consistent with previously published studies. 12 , 29 Serum Metabolic Traits A total of 159 serum samples from 53 critically ill patients (three samples per patient) were analyzed to investigate the serum metabolic traits of the non-TIC and TIC groups.

The MSC-E group exhibited significantly higher amplitudes than the DM group ( P < 0.001) and showed a trend toward higher amplitudes compared to the MSC and MSC-S groups, although these differences were not statistically significant ( P = 0.066 and 0.057, respectively) ( Fig. 5 b).

The EG showed a trend toward an abolition of the stress response, with lower cortisol levels than in healthy participants at all time points, especially 30 minutes after the onset of the stressor (MD = −0.14, 95% CI −0.28 to 0.00, p = 0.05).

32 In one physiological study, the area of the upper airway showed a trend to increase in patients treated with nasal expiratory positive airway pressure. 33 This effect could contribute to the clinical efficacy of NIV in acute hypoxaemic respiratory failure.

The period effect in the United States showed a trend of initially declining then rising, with a turning point around 2009.

Meanwhile, patients carrying LRRK2 G2019S at visit 1 showed a trend of downregulation of longer genes compared to shorter genes, but the test was not statistically significant (median length of upregulated genes, 12,216 bp; median length of downregulated genes, 17,417 bp; Wilcoxon P = 0.2509) (Extended Data Fig. 7b,c ).

In contrast, the control group’s medication adherence scores showed a trend of initial increase followed by decrease, which may reflect the influence of multiple factors on patients’ medication adherence without specific interventions, making it difficult to maintain a high level.

Cross-clamp time showed a trend towards longer duration in males (56.0 ± 17.6 min) vs. females (51.3 ± 15.1 min), though this difference did not reach statistical significance ( p = 0.069).

The FAD/chol cluster with poor prognosis showed a trend toward decreased prevalence of VHL mutations and higher c-MET copy numbers.

After specimen installation, the surface cavitation intensity showed a trend of initial increase followed by a decrease with increasing cavitation erosion distance.

For secondary collapse rates, Western studies (three studies, 295 patients) demonstrated a significantly higher risk with autografts compared to bone substitutes (RR = 1.45, 95%CI: 1.07, 1.97; P value = 0.02), while the single Asian study (74 patients) showed a trend in the opposite direction, however this was not statistically significant (RR = 0.56, 95%CI: 0.21, 1.50; P value = 0.25).

Presence of dyslipidemia (β −1.33, p-value = 0.122) and diabetes mellitus (β −1.82, p-value = 0.323) showed a trend of negative association with max.

In addition, when the RM particles were between 0.850 and 1.700 mm, the pellet strength showed a trend of first increasing and then decreasing with an increase in the proportion of large particles.

Analysis of the complete blood count showed a trend toward reduced circulating monocyte and neutrophil counts with BHB treatment; but these differences did not reach statistical significance.