Barely Significant
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“did not reach statistical significance”

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The higher BiP expression in the MU group was also supported by western blotting analysis, although the difference of the BiP/FLAG ratio did not reach statistical significance, probably due to the inclusion of FLAG-negative cells (BiP/FLAG, WT vs MU: P = 0.0198; BiP/Acitn, WT-H 2 O 2 vs MU-H 2 O 2 : P = 0.0102; Figure 4D ).
Although the change in fasting plasma glucose between the two IUGR groups weaned on the casein and whey diets did not reach statistical significance, the fasting plasma insulin was significantly higher in the IUGR group weaned on the whey diet than on the casein diet (+14%, p = 0.02; Figure 4 F).
After age stratification, in participants younger than 60 years, we found that the association between often playing computer games and a lower risk of ACP did not reach statistical significance (HR 0.393, 95% CI 0.175-0.844; P =.02; Table S12 in Multimedia Appendix 1 ).
Most results did not reach statistical significance; we only found a significant effect of the intervention in the IRR for fall-related injuries in the non-frail group ( p = 0.02).
For the distal radius ( Tables 3 and 4 ), the temporal changes in mean values of subregional mechanical parameters did not reach statistical significance except for E 22 (at 12 months) and G 23 (at 24 months) for the estradiol group, for which 6.1% ± 2.2% ( p = .02) and 3.8% ± 1.5% ( p = .04) increases were observed, respectively.
Thereafter, the plasma levels of mtDNA in the patient group continued to increase compared with those of the control group (t 72 ), but did not reach statistical significance (controls: 65 (28–119) copies/μL; patients: 281 (110–805) at t 0 , 403 (168–1937) at t 24 and 467 (188–952) copies/μL at t 72 ; controls vs. patients: p = 0.02 at t 0 , p = 0.03 at t 24 and p = 0.44 at t 72 ; Figure 1 B).
LAG-3 levels were also elevated in total CD3+ T lymphocytes and CD8+ effector T cells, but it did not reach statistical significance in CD4+ T cells (MFI: 213.8 ± 16.7 vs. 151.3 ± 8.3, p = 0.02, 290.1 ± 23.5 vs. 188.7 ± 14.2, p = 0.005 and 176.7 ± 17.78 vs. 132.9 ± 6.3, p = ns, respectively) ( Figure 4 A,D).
This outcome, whose individual components did not reach statistical significance, occurred in 35.5% of patients on treatment vs. 38.5% in the placebo group [relative risk (RR), 0.90; 95% confidence interval (CI), 0.82–0.98; P = 0.02]; 16.4% of patients on treatment and 17.5% of patients in the placebo arm died of cardiovascular causes (RR, 0.93; 95% CI, 0.81 to 1.06); 27.4% of patients on treatment and 29.6% in the placebo group were hospitalized for HF (RR, 0.90; 95% CI, 0.81–1.00).
Heart failure therapy: the fifth card.
Eur Heart J Suppl · 2023 · PMC10120986
Though our conversion rate was low in both arms, the robotic arm was favored but did not reach statistical significance (0.5% vs. 4.1%; RR, 0.21; 95% CI, 0.03 to 1.34; p=0.02) and may not reflect widespread conversion rates for laparoscopies performed for this indication ( Table 6 ).
After adjusting for age and smoking status, flicker-stimulated retinal arteriolar calibre change from baseline was associated with diabetes mellitus ( β = − 0.80, p < 0.0001) and flicker-stimulated venular calibre change from baseline ( β = 0.34, p = 0.0008), but this association did not reach statistical significance with reactive hyperaemia index ( β = 0.22, p = 0.02).