“did not reach statistical significance”

Although this finding did not reach statistical significance, a clear trend was observed.

Careful analysis in HCAECs showed a slight trend of decreasing oxLDL uptake after preincubation with increasing amounts of adiponectin, but this trend did not reach statistical significance.

We agree that the is a strong trend in our study in young NAION patients with Tobacco consumption, and although it did not reach statistical significance this may have been due to relatively low sample size.

Validation Analysis In a meta-analysis of 3 independent data sources, rs738409 G showed a trend for association with a reduced risk of COVID-19 hospitalization/severe disease vs mild disease; but the result did not reach statistical significance (additive OR: 0.83; 95% CI, 0.66–1.05; P = .12; P heterogeneity = .68) (see Figure 1 ).

And the gene expression levels of Cxcl12, Flt1, and Kdr were also significantly increased in the P-EVs group compared with the EVs group ( P < 0.05), while Tgfbr1 also showed an increasing trend, though this did not reach statistical significance (Figure 7 E).

Although in some models there was a clear trend in the decrease of IFNAR1 expression in M-MDSC as compared to Mon, it did not reach statistical significance (Fig. 1c ).

Although MDTM showed a trend toward an improved survival rate among patients with stage IV HNC, it did not reach statistical significance [combined HR = 0.81, 95% CI (0.59–1.10), Z = 1.35, P = 0.18, Figure 3 ].

NP-led MET calls showed a trend toward decreased mortality within 24 h of index MET call, but this did not reach statistical significance (3.4% vs. 7.2%, 0.47 (0.21–1.05); p = 0.06).

There was a strong trend, which however, did not reach statistical significance, towards a higher expression of DRD2 in GBM1 (70 (80–40)) than in the HCs (45 (54–40)).

In silico analysis of the Cancer Genome Atlas (TCGA) data including 412 chemotherapy-naive, invasive, high-grade urothelial tumors [ 3 ] using the Human Protein Atlas platform ( http://www.proteinatlas.org , accessed on 6 March 2021) showed a trend towards longer survival in UCB with high expression of GRHL3; however, it did not reach statistical significance ( Supplementary Figure S6 ) [ 24 ].

While we found there was a clear trend in PDGFR‐β immunoreactivity in the order: old controls >PSND > PSD (Figure 5 A), the mean values for PDGFR‐β assessed by ELISA did not reach statistical significance ( P > 0.05).

In a follow-up study by Dreyer et al., the same techniques found a favorable trend in ICP, CPP, and patient outcomes in the OMT cohort; however, they did not reach statistical significance [ 20 ].

The mRNA expression of CXCL10 also showed a decreasing trend in the HJ-treated group, although it did not reach statistical significance ( Fig. 5D , P=0.086).

A weak trend in the same direction was observed between the time spent looking at the target and localisation error although this did not reach statistical significance ( p = 0.128).

In the analysis for TIM3, CAR-αPD-1 and CD19 CAR-Trap showed a trend toward the inhibition of TIM3 upregulation, but it did not reach statistical significance ( Figure 5 D).

Eyes injected with Das-PLGA showed a trend for reduced expression of aSMA but the difference did not reach statistical significance (Table 2 ).

Although it did not reach statistical significance, the incidence of perioperative MIs showed a trend toward less MI rate in the Mini-Bypass group.

While treatment with emollient therapy showed a trend toward increased weight gain, especially in the younger patients (2 to < 6-months old), this effect did not reach statistical significance and time to clinical recovery from the acute phase of illness was not measurably impacted.

LV systolic function index (+dp/dt) showed a trend toward improvement but did not reach statistical significance ( P >.05).

Patients with MG and anti‐NRIP autoantibody showed a trend to have unstable MG course (requiring titration of MG‐specific medication within 1 year) compared with those without anti‐NRIP autoantibodies, although the difference did not reach statistical significance ( P = 0.077).

These differences were consistent with a numerical trend towards shorter disease duration and lower serum myoglobin in the CG, which did not reach statistical significance (Table 1 ).

47.0 (43.0–51.0) mm, p = n.s., p < 0.05) showed a trend for an age-dependent increase, however, the differences between age groups did not reach statistical significance.

As Figure 3 B shows, with regard to the cognitive domain, both groups evolved in parallel; however, unlike the placebo group, the melatonin plus zinc group showed a trend towards improvement that was maintained over the 16 weeks of treatment, although it did not reach statistical significance (16 weeks vs. baseline, p = 0.058).

In addition, a positive trend was observed when comparing T1 and T3 in APOE-ε4–; however, this association did not reach statistical significance.

Moreover, we observed an increasing trend of exacerbations in patients with T2 immunity, although these data did not reach statistical significance.