“did not reach statistical significance”

When analyzed as a continuous variable, the number of sessions (per 1 session increase) showed a trend towards a lower risk of all-cause mortality; however, this association did not reach statistical significance (HR 0.97; P=0.39).

In stratified analyses, patients with wider baseline QRS duration and female sex showed a numerical trend toward greater benefit with the AP strategy, although these findings did not reach statistical significance and should be interpreted cautiously.

While their study observed an increasing trend in implant failure rates from Stage I/II (0%) to Stage IV (6.5%), this trend did not reach statistical significance, suggesting that staging alone may not adequately predict implant failure.

Sex showed a borderline association (β = 0.484, OR = 1.62, p = 0.056), indicating a possible trend toward sex-related differences that did not reach statistical significance.

Serum albumin level showed a trend toward an inverse association, but this did not reach statistical significance after adjustment (OR 0.927 per 1 g/L increase, 95% CI 0.854–1.006; p = 0.069) (Table 4 ).

Similarly, the Systemic Immune-Inflammation Index (SII) [neutrophil × platelet/lymphocyte] showed an increasing trend in ICU-admitted patients; however, this did not reach statistical significance, possibly due to the limited sample size and heterogeneity of the study population [ 22 ].

The association with heart failure showed a strong trend but did not reach statistical significance (AOR: 4.92, 95% CI: 0.87-27.6; p = 0.070).

In addition, foam cell-associated markers such as Cd9 , Spp1 significantly downregulated following Cebpb knockout, while Mmp12 showed a decreasing trend that did not reach statistical significance.

While lower DDS showed a trend toward increased frailty, it did not reach statistical significance in this specific model after adjusting for all covariates.

In terms of safety, IVT was significantly associated with an increased risk of sICH; although the risk of mortality in the IVT group showed an increasing trend, this difference did not reach statistical significance.

Although the Immediate-iPCMT condition showed a trend towards improvement in student-educator relationship closeness and perceived student conduct problems, these pre- to post-intervention differences did not reach statistical significance.

However, certain subtypes, particularly L747_A750delinsP, showed a trend toward a shorter PFS compared with the common E746_A750del subtype, although these differences did not reach statistical significance (12.3 months vs. 24.3 months; P = 0.100).

As mentioned before, our results are not fully consistent with this, but we did observe a decreasing trend for VDR after 12 h of treatment with 25D which did not reach statistical significance.

In contrast, for OS, perforation (HR: 2.38, 95% CI: 0.96–5.88, p = 0.06) and pT4 (HR: 2.11, 95% CI: 0.86–5.14, p = 0.1) did not reach statistical significance but showed a trend toward worse prognosis.

In terms of sex differences, Wdr26 +/– male mice spent a significantly reduced percentage of time in the target quadrant ( Supplemental Figure 2G ), whereas a decreasing trend was observed among female mice, although it did not reach statistical significance ( Supplemental Figure 2H ).

In addition, Sirt1 knockdown showed a trend toward a 17.58% increase in the p-p65/p65 ratio compared with the Bmal1 overexpression group, although the difference did not reach statistical significance ( Figure 5D ).

The control group showed a trend towards a decline in ALBI scores, but did not reach statistical significance at 12 months (P=0.11).

Comparison of cell-type composition revealed that the proportion of CD25 + cells within the CD4+ T cell compartment showed an increasing trend in non-survivors compared with survivors at both the sample and cell levels, although this difference did not reach statistical significance (Additional file 2: Figure S3).

A platelet count ≥100×10 9 /L, aspartate aminotransferase < 80 U/L, lactate dehydrogenase <500 U/L, and receipt of anti-tumor therapy showed a trend toward better survival but did not reach statistical significance ( P = 0.086, P = 0.075, P = 0.059, and P = 0.080, respectively).

Although both normal weight (OR = 0.25,95% CI:0.06 ~ 1.03, p = 0.05) and overweight (OR = 0.11, 95% CI:0.01 ~ 1.25, p = 0.08) groups showed a trend toward reduced risk compared to the underweight reference group, these associations did not reach statistical significance in multivariable model.

Although the differences in positivity rates across dormitories did not reach statistical significance after adjustment for multiple comparisons, the data nonetheless indicated a pronounced trend toward concentrated infection intensity in specific rooms, particularly those allocated to Class 2302.

Cys-C levels showed a decreasing trend following AVLE treatment, although the difference did not reach statistical significance ( Figure 1I ).

Although a decreasing trend in severe hypoxia was observed in the oliceridine group, the difference did not reach statistical significance.

HER2 status showed a trend toward association with survival but did not reach statistical significance ( p = 0.058).

Thereby, PD-L1/ErbB2.CAR NK-92 cells showed a trend toward more pronounced degranulation, although this did not reach statistical significance.