“a pronounced trend”

Asthma presented a pronounced trend, with an overall prevalence of 3.2%, notably high in 2012 (6.1%) but reduced to 1.8% by 2015, with significant year-to-year differences ( p = 0.002).

Notably, the patients with high HLA-B HED showed a pronounced trend towards prolonged OS (Fig. 3c , log-rank test p = 0.041) and PFS (Fig. 3d , log-rank test p = 0.18).

Following adjustments for age, WHO grade, and extent of resection, diabetes persisted as a significant independent predictor of tumor recurrence (adjusted HR = 8.92; 95%CI: 1.73-45.87; P = 0.009) and exhibited a pronounced trend towards elevated mortality (adjusted HR = 10.12, 95%CI: 1.00-102.55; P = 0.048).

Although peak AST and ALT levels did not differ significantly between the groups, there was a pronounced trend toward higher median AST levels in the FHH+ group (1597 vs. 771, p = 0.050).

In the current work, we also detected a pronounced trend in the reduction ( P = 0.0571) of PMN migration after infecting T84 cells in the absence of AAT with the Δ sepA strain compared to WT Shigella .

There was a pronounced trend ( p = 0.058) between control cells and cells treated with 100 nM E2 ( Fig 9C ).

Notably, the 3-way interaction training order × test time × trial type showed a pronounced trend, F (1, 30) = 3.86, p = 0.059, η 2 g = 0.01, indicating that participants in the random DT training condition slightly improved TOC in terms of error rates in task 1 (difference of error rate in random-order blocks minus fixed-order blocks) from pre-to post-test ( m difference pre-minus post-test = 0.6%), while participants in the fixed DT training condition demonstrated a decline in error-based performance ( m difference pre-minus post-test = −2.2%).

Moreover, although when taking the AA genotype as a reference, we found that AG + GG genotype was not statistically significantly associated with the risk of WT, there was a pronounced trend that carriers of 1 variant combined genotype had an increasing risk of WT (OR=0.6, 95%CI: 0.38–1.03; P =0.065).

The normal copy number of topoisomerase 1 in patients treated with the CAX scheme was associated with a lack of response to treatment in 85.7% of patients (6/7 cases, p = 0.03); 50% of patients with a thymidylate synthase deletion responded to the CAX treatment, while in patients with stabilization and progression, no deletions were observed (the relationship was at the level of a pronounced trend, p = 0.07) ( Table 3 ).

The result is not statistically significant, but a pronounced trend is shown at p = 0.07 ( Figure 4 A).

Further, it was shown that in the general group of patients with the presence of deletions (25.5%, 12/47 patients) and amplifications (31.9%, 15/47 patients) at the level of a pronounced trend ( p = 0.07), an objective response is most often observed on treatment (complete and partial regression), compared with the group without response (stabilization and progression), where the frequency of deletions (10.5%, 2/19 patients) and amplifications (15.8%, 3/19 patients) is lower, more than twice ( Table 2 ).

Notably, while BST2 expression showed a pronounced trend toward an association with advanced FIGO stage, this correlation did not reach statistical significance ( p = 0.075).

Again, NP cells showed a pronounced trend toward higher reactivity ( p = 0.08).

A pronounced trend indicating increased mucosal healing was identified within the familial cohort (73.3% versus 55%, p = 0.093).

The sites do not show a pronounced trend of changing environmental conditions, despite expectations of a shift from brackish to marine conditions due to rising sea levels and changing salinity [ 47 ].

The insomnia group exhibited a markedly higher predicted brain age compared to chronological age (uncorrected mean BAG = 8.10 years; age-adjusted mean BAG = 1.60 years; both p < 0.001), indicating a pronounced trend of advanced brain aging and accelerated decline.

Overall, FB and SB exhibited relatively stable soluble protein levels throughout the developmental stages, whereas LB showed a pronounced trend of initial decline followed by a marked increase.

Finally, we observed a pronounced trend towards a decrease in ENSA levels in the substantia nigra of PD patients.

Ecdysozoan Apoptosis Complexity Is Depleted More Than Nonapoptosis Gene Content We observed a pronounced trend of decreasing apoptosis gene complements among the ecdysozoan genomes utilized in this study ( fig. 3 ).

The basal group displayed high reconstructed values for the mean drift parameter (α), emphasizing a pronounced trend to larger body sizes.

However, results derived from the model predicted that large regions in the Atlantic domain might have experience increases in the development rate of up to 60%-80% and a more than 80% increase in the survival rates during developing and questing stages, which could be driven by a pronounced trend in temperature increase in the last 20–30 years [ 54 – 56 ].

We observed a pronounced trend in which APA events involving 3′ UTR shortening significantly outnumbered those showing 3′ UTR lengthening.

( 14 ) similarly observed in their bibliometric analysis of nursing AI trends that research focus has expanded from foundational education to medical record management and intelligent decision support, revealing a pronounced trend toward cross-domain integration.

Because of the small sample size of our cohorts, it did not yield many statistically significant results, but from the available data, a pronounced trend showed that female patients receiving immunotherapy in both first‐ and second‐line therapies tended to achieve potentially longer survival and better response.

As depicted in the above revolution review, electrochemical vibration sensors exhibit a pronounced trend toward structural unification and MEMS-based manufacturing methodologies.