In addition, a positive trend was observed when comparing T1 and T3 in APOE-ε4–; however, this association did not reach statistical significance.
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In the literature
Cavβ1b was able to significantly increase the surface pool of WT-Cav1.2-HA (10145 +/-790 ALUs, p = < 0.05 ANOVA), and there was a strong trend towards increased surface expression of A39V-Cav1.2 (10109 +/-842 ALUs), however, this effect did not reach statistical significance (also see Additional file 2 : Figure S2).
Kaplan-Meier survival analysis showed a trend toward prolonged survival in the MSLN-1 F-NK group compared to 1 F-NKs, though the p-value did not reach statistical significance ( p = 0.0625) (Fig. 6 G).
Receipt of adjuvant therapy showed a trend toward improved PFS, although this did not reach statistical significance (51.7 vs. 21.1 months, p = 0.051).
Median CD4 + /CD8 + ratio showed a trend toward improvement from baseline (0.83 [IQR, 0.70–1.00]) to 48 weeks postswitch to dolutegravir plus lamivudine (0.86 [IQR, 0.68–1.06]) but did not reach statistical significance ( P = .060).
Children who used inverted contrast settings on electronic devices showed a trend for lower SE progression compared to those using standard contrast settings, although this difference did not reach statistical significance (Student’s t test, p = 0.214; – 0.11 D vs. – 0.23 D, respectively, see Supplementary Fig. 1).
miR-100a and miR-10 were significantly increased in the pancreatic cancer patients compared to non-cancer controls while a number of the other miRs (miR-16, 21, 155, 199, 221, and 223) showed a trend of increased expression that did not reach statistical significance ( Figure 5A ).
Tumour grade showed a trend towards reduced survival with increasing dedifferentiation, with colorectal cancer related deaths occurring in 34.5% (10/29), 48.4% (171/353) and 56.3% (40/71) of patients with well, moderately and poorly differentiated tumours respectively, although this did not reach statistical significance in our cohort of patients.
In the BAL from LPS-challenged mice, treatment with ACT-1004-1239 significantly reduced LPS-induced CXCR3 + lymphoid cell recruitment ( Figure 3C ) and showed a trend to decrease the late recruitment of the few CXCR3 + myeloid cells induced by LPS, although this did not reach statistical significance ( Figure 3D ).
The differences did not reach statistical significance, but presented an interesting trend.
A decreasing trend in immune cell number was observed in the sample treatment groups compared to the LPS group, although this trend did not reach statistical significance ( Fig. 4A - 4D ).
Although their study suggested a slight trend toward greater dermal and subcutaneous thickness on the subcutaneous side, these differences did not reach statistical significance, likely due to the small sample size ( n = 6).
A slight trend toward increased inflammatory markers (CRP, IL-6, and the proportion of immature neutrophils) was observed in patients with higher CIRS-G scores, although differences did not reach statistical significance (Fig. 3 a-i).
While the presence of CMBs showed a trend towards higher odds of HT, the association did not reach statistical significance patients receiving EVT only.
Patients with genotype “ FLT3-ITD + /NPM1 - ” showed a trend of poor EFS compared with those without the cytogenetic characteristic, but it did not reach statistical significance ( P = 0.089; Fig. 1f ).
Five-day CT showed a trend toward a higher eradication rate than STT, although the difference did not reach statistical significance.
At 3 months there was a clear trend towards a decrease in pain during activity (-3 mm vs placebo) observed in all three studies although this effect did not reach statistical significance (Fig. 4 ).
Besides, there seemed to be a decreasing trend of total cholesterol, while showed an increasing trend of HDL-cholesterol at all time points (although the results did not reach statistical significance).
In addition, edema and inflammation both showed a trend towards elevated scores nine hours after induction of pancreatitis in EPPK −/− mice; however, the difference did not reach statistical significance with p = 0.08 and p = 0.16, respectively ( Fig. 4I ).
Second, there was a weak trend indicating that higher symptom severity at admission, as measured by the HoNOS score, might be associated with increased dropout risk (OR 1.07, 95% CI 0.99-1.15; P =.08), though this finding did not reach statistical significance ( Table 3 ).
In the subgroup of participants with poor diet quality (HEI-2015 < 60), the association between observed ASVs and RA showed a trend toward significance, but did not reach statistical significance ( P = 0.094).
In contrast, patients with PE exhibited significantly higher methylation levels in T compared with D tissues ( p = 0.035), while A tissues showed a trend toward higher methylation compared with D tissues, although this difference did not reach statistical significance ( p = 0.052).
In non-obese subjects, the CT+CC group showed a trend toward higher sodium intake scores and total moderation scores compared to the TT group; however, these associations did not reach statistical significance after applying the corrected p -level for stratified analyses.
a positive trendgold
Pielou evenness, which reflects the uniformity of species distribution within the microbial community, showed a positive trend with age but did not reach statistical significance ( p = 0.17).
Although differences did not reach statistical significance, a trend towards significance was strongest for the left and right SLF parietal sections.