“did not reach statistical significance”

Additionally, we analyzed the Gene Expression Omnibus (GEO) database ( GSE83452 ) and found that the expression of SELE was significantly elevated in the livers of MASH patients, while ICAM-1 expression showed an increasing trend but did not reach statistical significance (Fig.

In contrast, attendance at health centers showed a trend toward reduced odds (aOR = 0.26, 95% CI 0.05–1.23), although this did not reach statistical significance ( p = 0.09).

The MBOA group showed a trend of longer-term improvement in loneliness at T3, but the modest magnitude of change did not reach statistical significance compared with the SCC group, in which no such trend was observed.

30 , 31 Iron deficiency demonstrated a significant association with oral cancer (RR = 1.067, 95% CI: 1.002-1.136, P = .042), while its association with periodontitis showed a positive trend but did not reach statistical significance (RR = 1.026, 95% CI: 0.996-1.057).

The expression levels of inflammatory factors (IL‐6, IL‐1 β , and TNF‐ α ) in the hippocampus of low BBR dose mice indicated a decreasing trend compared to the LPS group; however, this difference did not reach statistical significance (Figure 5 E–G).

RT-qPCR results demonstrated that the mRNA expression levels of ACACA and ACLY in the Sj group were significantly higher than those in normal liver tissues ( P < 0.05), and the mRNA expression of all three genes showed a trend of “Sj group > HBV group > normal control group” (though the intergroup differences did not reach statistical significance).

ERG recordings also showed a trend toward reduced b-wave amplitudes in the 0.01 DA test, although this difference did not reach statistical significance ( Figs. 4 C, 4 D, P = 0.61).

Other features showed a trend toward the predicted direction but did not reach statistical significance using a conservative bootstrapping technique.

Notably, although the pooled analysis did not reach statistical significance, the meta-analysis showed a numerical trend toward increased risk (OR 1.37) accompanied by very high between-study heterogeneity (I2 = 87.2%).

In contrast, in patient aged ≥ 80 years, the OS benefit associated with maximal resection showed a favorable trend but did not reach statistical significance ( p = 0.11, Fig. 3 C).

The multifactor ANOVA further supported these findings, demonstrating that tumor size ( p < 0.001) and SI motion ( p < 0.001) have a highly significant influence on registration quality, whereas the respiratory cycle and AP/LR motions did not reach statistical significance ( p > 0.05).

Supernatants from microglia exposed to EVs loaded with let-7e or miR-548b-3p showed an increasing trend of TNF release, however, those TNF release levels did not reach statistical significance.

Hypertension showed a trend toward association but did not reach statistical significance.

Weekly intercourse frequency showed a trend toward being lower in the SPE group but did not reach statistical significance ( P = 0.062).

For changes in total palatal volume (ΔTV), sagittal displacement of the maxillary central incisors relative to the vertical reference line (ΔU1⊥VRL) showed a positive trend toward volumetric increase, although this association did not reach statistical significance ( p = 0.068).

GluN2B expression also showed a trend toward a decrease; however, this change did not reach statistical significance (Fig. 7a, c ).

The proportion of helper T cells (CD3 + CD4 + ) showed a decreasing trend but did not reach statistical significance (Fig. 5 C and G).

Functional status Within-group analysis in the TECAR group showed a trend toward improved lower extremity functional scores over time, although this change did not reach statistical significance (p=0.058).

Significant differences were observed between the two subtypes in terms of sex ( p = 0.003), PSQI ( p = 0.0004), SAS ( p < 0.0001), and SDS ( p < 0.0001), whereas age showed a trend toward difference but did not reach statistical significance ( p = 0.064) ( Table 2 ).

In this cohort, DLRT showed a trend towards better survival than CLSLRT in RLD patient undergoing lung retransplantation for BOS, although this did not reach statistical significance.

Co-localization of BNIP3, BNIP3L and phospho-BNIP3L with mitochondria basally showed a trend toward being reduced, however, due to large variability between both controls and patients this did not reach statistical significance ( Figure 5 and Supplementary Figure 6 ).

The length of hospital stay showed a slight increase in the risk of infection-related mortality, with an odds ratio of 1.014 (95% CI: 0.998–1.030); however, this association did not reach statistical significance (p=0.078), indicating only a trend towards significance.

For the primary endpoint of all-cause mortality or HF readmission, the NSAIDs-related group showed a trend toward improved outcomes, although the difference did not reach statistical significance (hazard ratio [HR] 0.569, 95% confidence interval [CI] 0.289–1.118; p = 0.102).

Notably, the low-dose rhCol III group (5 μg/mL) showed a trend toward reduced ROS fluorescence but did not reach statistical significance ( p = 0.0554), which may reflect a smaller effect size at low exposure, limited statistical power, and the known methodological limitations and sensitivity of commonly used fluorescent probes ( 68 , 69 ).

A slight trend of higher plasma corticosterone concentrations in 3xTg-AD mice was observed, although it did not reach statistical significance ( p > 0.05). 3.3.